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In cases associated with sudden discontinuation of MAO inhibitors (MAOIs), acute psychosis has been observed. [2] [11] [12] Over fifty symptoms have been reported. [13] The SNRI venlafaxine has been reported to have a higher incidence in withdrawal symptoms after discontinuation when compared to other SNRIs. [14]
Serotonin reuptake inhibitors should not be abruptly discontinued after extended therapy, and whenever possible, should be tapered over several weeks to minimize discontinuation-related symptoms which may include nausea, headache, dizziness, chills, body aches, paresthesias, insomnia, and brain zaps. Paroxetine may produce discontinuation ...
Sertraline, sold under the brand name Zoloft among others, is an antidepressant medication of the selective serotonin reuptake inhibitor (SSRI) class [10] used to treat major depressive disorder, generalized anxiety disorder, social anxiety disorder, obsessive–compulsive disorder (OCD), panic disorder, and premenstrual dysphoric disorder. [11]
MAOIs are an older class of antidepressants, primarily used in the 20th century. Because of their side effects and interaction risk, most MAOIs have been replaced by newer antidepressants over the ...
As for the Zoloft side effect in women, the most common intimacy side effect of sertraline and other SSRIs is a lower level of interest in intimacy and difficulty climaxing.
Approximately 3% of healthy elderly persons living in the community have major depression. Recurrence may be as high as 40%. Suicide rates are nearly twice as high in depressed patients as in the general population. Major depression is more common in medically ill patients who are older than 70 years and hospitalized or institutionalized.
Upon the discontinuation of serotonergic drugs, most cases of SS resolve within 24 hours, [6] [9] [73] [74] although in some cases delirium may persist for a number of days. [31] Symptoms typically persist for a longer time frame in patients taking drugs which have a long elimination half-life , active metabolites, or a protracted duration of ...
Medications like antidepressants are highly effective for treating depression, as they work to balance serotonin and other brain chemicals. However, there’s no one-size-fits-all approach.