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  2. Cephalosporin - Wikipedia

    en.wikipedia.org/wiki/Cephalosporin

    For example, the fourth generation of cephalosporins is not recognized as such in Japan. [citation needed] In Japan, cefaclor is classed as a first-generation cephalosporin, though in the United States it is a second-generation one; and cefbuperazone, cefminox, and cefotetan are classed as second-generation cephalosporins.

  3. List of antibiotics - Wikipedia

    en.wikipedia.org/wiki/List_of_antibiotics

    Cephalosporins (Fourth generation) Cefepime: Maxipime: Covers pseudomonal infections. Gastrointestinal upset and diarrhea; Nausea (if alcohol taken concurrently) Allergic reactions; Same mode of action as other beta-lactam antibiotics: disrupt the synthesis of the peptidoglycan layer of bacterial cell walls. Cephalosporins (Fifth generation ...

  4. Cefepime - Wikipedia

    en.wikipedia.org/wiki/Cefepime

    Cefepime is a fourth-generation cephalosporin antibiotic. Cefepime has an extended spectrum of activity against Gram-positive and Gram-negative bacteria , with greater activity against both types of organism than third-generation agents.

  5. List of β-lactam antibiotics - Wikipedia

    en.wikipedia.org/wiki/List_of_β-lactam_antibiotics

    The β-lactam core structures. (A) A penam.(B) A carbapenam.(C) An oxapenam.(D) A penem.(E) A carbapenem.(F) A monobactam.(G) A cephem.(H) A carbacephem.(I) An oxacephem. This is a list of common β-lactam antibiotics—both administered drugs and those not in clinical use—organized by structural class.

  6. Discovery and development of cephalosporins - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    The basic structure of 3rd generation cephalosporins. The majority of third generation cephalosporins have the aminothiazole group at position C-7. Different groups are found at the 7-α-position like 7-α-iminohydroxy and 7-α-iminomethoxy groups. Ceftibuten however possesses a 7-α-ethylidene group. This group gives ceftibuten higher ...

  7. Cefpirome - Wikipedia

    en.wikipedia.org/wiki/Cefpirome

    Cefpirome is a fourth-generation cephalosporin. Trade names include Cefrom, Keiten, Broact, and Cefir. Trade names include Cefrom, Keiten, Broact, and Cefir. Cefpirome is considered highly active against Gram-negative bacteria , including Pseudomonas aeruginosa , and Gram-positive bacteria .

  8. Cefquinome - Wikipedia

    en.wikipedia.org/wiki/Cefquinome

    Although fourth-generation cephalosporin resistance is very rare, they are active against bacteria carrying the AmpC-type β-lactamase resistance mechanism. Since the late 1990s, the US and EU have surveyed and gathered data for fourth-generation cephalosporins for both human and veterinary use.

  9. β-Lactam antibiotic - Wikipedia

    en.wikipedia.org/wiki/Β-Lactam_antibiotic

    β-Lactam antibiotics are indicated for the prevention and treatment of bacterial infections caused by susceptible organisms. At first, β-lactam antibiotics were mainly active only against gram-positive bacteria, yet the recent development of broad-spectrum β-lactam antibiotics active against various gram-negative organisms has increased their usefulness.