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Orphenadrine (sold under many brand names) [1] is an anticholinergic drug of the ethanolamine antihistamine class; it is closely related to diphenhydramine. It is a muscle relaxant that is used to treat muscle pain and to help with motor control in Parkinson's disease , but has largely been superseded by newer drugs.
Mebeverine is an anticholinergic but its mechanism of action is not known; it appears to work directly on smooth muscle within the gastrointestinal tract and may have an anaesthetic effect, may affect calcium channels, and may affect muscarinic receptors.
Other common spasmolytic agents include: methocarbamol, carisoprodol, chlorzoxazone, cyclobenzaprine, gabapentin, metaxalone, and orphenadrine. Thiocolchicoside is a muscle relaxant with anti-inflammatory and analgesic effects and an unknown mechanism of action.
This has varying benefits for dogs depending on their lifestyle. In some dogs, it aids in digestion by preventing constipation, in others it acts to improve satiety and encourage weight loss. [21] Flaxseed is also a good source of omega-3 and omega-6 fatty acids which have multiple health benefits for the animal such as improving coat quality. [21]
Constipation is a bowel dysfunction that makes bowel movements infrequent or hard to pass. [2] The stool is often hard and dry. [4] Other symptoms may include abdominal pain, bloating, and feeling as if one has not completely passed the bowel movement. [3] Complications from constipation may include hemorrhoids, anal fissure or fecal impaction. [4]
A number of other drugs, such as antipsychotics and the tricyclic family of antidepressants, have incidental muscarinic antagonist activity which can cause unwanted side effects such as difficulty urinating, dry mouth and skin, and constipation.
2. Lenny’s Grill & Subs. Lenny’s, a sub chain with about 100 locations across the South, is so close to serving a great meatball sub. The bread is just right.
The generic is a combination of 385 mg of paracetamol, 25 mg of orphenadrine citrate [1] and 30 mg of caffeine. [2] It was discontinued in the United States by the Food and Drug Administration in October 2015 [3] but is still available in Scandinavia, Austria, Greece, Thailand, Australia and Hong Kong. [citation needed]