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Drosophila melanogaster possesses a comparatively simple gut microbiota, consisting of only few bacterial species, mainly from two bacterial taxonomic groups: Bacillota and Pseudomonadota. [ 3 ] [ 4 ] The most common species belong to the families Lactobacillaceae (abundance of approx. 30%, members of the Bacillota) and Acetobacteraceae (approx ...
Drosophila is being used as a genetic model for several human diseases including the neurodegenerative disorders Parkinson's, Huntington's, spinocerebellar ataxia and Alzheimer's disease. [86] The fly is also being used to study mechanisms underlying aging and oxidative stress , immunity , diabetes , and cancer , as well as drug abuse .
Drosophila melanogaster has two Cdc25s, known as string and twine, which control mitosis [8] and meiosis, [9] respectively. Most other model organisms examined have three Cdc25s, designated Cdc25A, Cdc25B, and Cdc25C. An exception is the nematode Caenorhabditis elegans, which has four distinct Cdc25 genes (Cdc-25.1 to Cdc-25.4). [10]
Drosophila melanogaster sigmavirus (DMelSV) was discovered by a group of French researchers in 1937 [3] after they observed certain fly lines became paralysed and died on exposure to carbon dioxide (which is commonly used as an anesthetic for Drosophila).
The Drosophila Interactions Database (DroID) is an online database of Drosophila gene and protein interactions. [1] It was developed by Russell L. Finley's laboratory at Wayne State University School of Medicine in 2008 and has been funded by the National Human Genome Research Institute, National Institutes of Health's National Center for Research Resources, Michigan Proteome Consortium, and ...
The best known species of the Drosophilidae is Drosophila melanogaster, within the genus Drosophila, also called the "fruit fly." Drosophila melanogaster is used extensively for studies concerning genetics, development, physiology, ecology and behaviour. Many fundamental biological mechanisms were discovered first in D. melanogaster. [2]
Germ-band extension is a morphogenic process widely studied in the development of Drosophila melanogaster in which the germ-band, which develops into the segmented trunk of the embryo, approximately doubles in length along the anterior-posterior axis while subsequently narrowing along the dorsal-ventral axis. [1]
Scaptomyza flava, herbivorous leaf miner fly nested in the Drosophila, and a close relative of D. melanogaster. [41] Scathophaga stercoraria (the yellow dung fly), used to study sexual selection and sexual conflict; Schmidtea mediterranea (freshwater planarian), a model for regeneration and development of tissues such as the brain and germline