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Alternative online IC50 calculator (www.ic50.org) based on Python, NumPy, SciPy and Matplotlib; ELISA IC50/EC50 Online Tool (link seems broken) IC50 to pIC50 calculator; Online tool for analysis of in vitro resistance to antimalarial drugs; IC50-to-Ki converter of an inhibitor and enzyme that obey classic Michaelis-Menten kinetics
Lipophilic efficiency [1] (LiPE), sometimes referred to as ligand-lipophilicity efficiency (LLE) is a parameter used in drug design and drug discovery to evaluate the quality of research compounds, linking potency and lipophilicity in an attempt to estimate druglikeness.
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Ligand efficiency is a measurement of the binding energy per atom of a ligand to its binding partner, such as a receptor or enzyme. [1]Ligand efficiency is used in drug discovery research programs to assist in narrowing focus to lead compounds with optimal combinations of physicochemical properties and pharmacological properties.
Inhibitors have IC50 values so I tried to reintegrate it with information already present in the article. I think that including it in the lead paragraph would mislead people into thinking it was a discussion about inhibitors not The IC50 concept Lilypink 19:04, 5 November 2007 (UTC) IC50 is not a pharmacological constant! pA2 is a constant.
The tissue response (y-axis) to an agonist, in log concentration (x-axis), in the presence of different antagonist concentrations. The EC 50 of the agonist is represented by the x co-ordinate that corresponds with the half-maximum of the leftmost curve.
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