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The value obtained is largely dependent on the susceptibility of the microorganism and the antimicrobial potency of the chemical, but other variables can affect results too. [5] The MIC is often expressed in micrograms per milliliter (μg/mL) or milligrams per liter (mg/L).
In England, a single pub measure (25 ml (0.85 US fl oz)) of a spirit contains one unit. However, a larger 35 ml (1.2 US fl oz) measure is increasingly used (and in particular is standard in Northern Ireland [37]), which contains 1.4 units of alcohol at 40% ABV. Sellers of spirits by the glass must state the capacity of their standard measure in ml.
The American Twelfth (10 2 ⁄ 3 US oz [315 mL], or 1 ⁄ 12 of a US gallon), American Commercial Pint (12.8 US fl oz [379 mL], or 1 ⁄ 10 of a US gallon) / British Reputed Pint (13 1 ⁄ 3 imp oz [379 mL], or 1 ⁄ 12 an Imperial gallon), and the Canadian "stubby" bottle (12 imp oz [341 mL]) may have been factors.
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A rough conversion between specific gravity, SG, and either degrees Brix, Plato or Balling can be made by dividing the thousandths of SG above 1 (which is often referred to as gravity points) by 4. So a specific gravity of 1.048 has 48 gravity points, and 48 divided by 4 would be approximately 12 degrees Plato, Balling or Brix.
[1] [2] [3] It is defined as the number of millilitres (mL) of pure ethanol present in 100 mL (3.5 imp fl oz; 3.4 US fl oz) of solution at 20 °C (68 °F). The number of millilitres of pure ethanol is the mass of the ethanol divided by its density at 20 °C (68 °F), which is 0.78945 g/mL (0.82353 oz/US fl oz; 0.79122 oz/imp fl oz; 0.45633 oz ...
Threshold dose is the minimum dose of drug that triggers minimal detectable biological effect in an animal. [1] At extremely low doses, biological responses are absent for some of the drugs. The increase in dose above threshold dose induces an increase in the percentage of biological responses. [ 2 ]
A particularly important instance arises in toxicology, where the model for the effect of a drug may be that there is zero effect for a dose below a critical or threshold value, while an effect of some significance exists above that value. [1] Certain types of regression model may include threshold effects. [1]