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The term significance does not imply importance here, and the term statistical significance is not the same as research significance, theoretical significance, or practical significance. [ 1 ] [ 2 ] [ 18 ] [ 19 ] For example, the term clinical significance refers to the practical importance of a treatment effect.
Although this p-value objectified research outcome, using it as a rigid cut off point can have potentially serious consequences: (i) clinically important differences observed in studies might be statistically non-significant (a type II error, or false negative result) and therefore be unfairly ignored; this often is a result of having a small ...
In broad usage, the "practical clinical significance" answers the question, how effective is the intervention or treatment, or how much change does the treatment cause. In terms of testing clinical treatments, practical significance optimally yields quantified information about the importance of a finding, using metrics such as effect size, number needed to treat (NNT), and preventive fraction ...
Meta-research is the study of research through the use of research methods. Also known as "research on research", it aims to reduce waste and increase the quality of research in all fields. Meta-research concerns itself with the detection of bias, methodological flaws, and other errors and inefficiencies.
Clinical research is different from clinical practice: in clinical practice, established treatments are used to improve the condition of a person, while in clinical research, evidence is collected under rigorous study conditions on groups of people to determine the efficacy and safety of a treatment.
The unit of analysis should also not be confused with the unit of observation.The unit of observation is a subset of the unit of analysis. [citation needed] A study may have a differing unit of observation and unit of analysis: for example, in community research, the research design may collect data at the individual level of observation but the level of analysis might be at the neighborhood ...
Difference in differences (DID [1] or DD [2]) is a statistical technique used in econometrics and quantitative research in the social sciences that attempts to mimic an experimental research design using observational study data, by studying the differential effect of a treatment on a 'treatment group' versus a 'control group' in a natural experiment. [3]
Content usually takes the form of articles presenting original research, review articles, or book reviews.The purpose of an academic journal, according to Henry Oldenburg (the first editor of Philosophical Transactions of the Royal Society), is to give researchers a venue to "impart their knowledge to one another, and contribute what they can to the Grand design of improving natural knowledge ...