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  2. T helper cell - Wikipedia

    en.wikipedia.org/wiki/T_helper_cell

    Additional populations of memory T cells are now known to exist. These include tissue-resident memory T (Trm) cells and virtual memory T cells. [35] The single unifying theme for all memory T cell subtypes is that they are long-lived and can expand quickly to large numbers of effector T cells upon encountering their cognate antigen.

  3. T cell - Wikipedia

    en.wikipedia.org/wiki/T_cell

    Unlike CD8 + killer T cells, the CD4 + helper T (T H) cells function by further activating memory B cells and cytotoxic T cells, which leads to a larger immune response. The specific adaptive immune response regulated by the T H cell depends on its subtype (such as T-helper1, T-helper2, T-helper17, regulatory T-cell), [ 4 ] which is ...

  4. Memory T cell - Wikipedia

    en.wikipedia.org/wiki/Memory_T_cell

    Antigen-specific memory T cells specific to viruses or other microbial molecules can be found in both central memory T cells (T CM) and effector memory T cells (T EM) subsets. . Although most information is currently based on observations in the cytotoxic T cells (CD8-positive) subset, similar populations appear to exist for both the helper T cells (CD4-positive) and the cytotoxic T ce

  5. CD4 - Wikipedia

    en.wikipedia.org/wiki/CD4

    T-cells play a large part in autoinflammatory diseases. [25] When testing a drug's efficacy or studying diseases, it is helpful to quantify the amount of T-cells on fresh-frozen tissue with CD4+, CD8+, and CD3+ T-cell markers (which stain different markers on a T-cell – giving different results). [26]

  6. Tissue-resident memory T cell - Wikipedia

    en.wikipedia.org/wiki/Tissue-resident_memory_T_cell

    Also, not every T RM express CD69 and CD103 what support phenotypic heterogeneity of T RM cells. [18] T RM cells are able to activate innate and adaptive leukocytes to protect the host. [27] [2] [28] [29] Cooperation of T RM cells with other memory T cell populations provide tissue surveillance and clearance of the infections. [30] [31] [12]

  7. Cell-mediated immunity - Wikipedia

    en.wikipedia.org/wiki/Cell-mediated_immunity

    Type 1 immunity consists of these cells: [5] CD4+ T H 1 cells; CD8 + cytotoxic T cells (T c 1) T-Bet + interferon gamma producing group 1 ILCs(ILC1 and Natural killer cells) CD4 + T H 1 Cells. It has been found in both mice and humans that the signature cytokines for these cells are interferon gamma and lymphotoxin alpha.

  8. Naive T cell - Wikipedia

    en.wikipedia.org/wiki/Naive_T_cell

    In immunology, a naive T cell (T h 0 cell) is a T cell that has differentiated in the thymus, and successfully undergone the positive and negative processes of central selection in the thymus. Among these are the naive forms of helper T cells ( CD4 + ) and cytotoxic T cells ( CD8 + ).

  9. Priming (immunology) - Wikipedia

    en.wikipedia.org/wiki/Priming_(immunology)

    Priming of naive CD8 T cells generates cytotoxic T cells capable of directly killing pathogen-infected cells. CD4 cells develop into a diverse array of effector cell types depending on the nature of the signals they receive during priming. CD4 effector activity can include cytotoxicity, but more frequently it involves the secretion of a set of ...

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