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Its use during pregnancy can bring harm to the developing fetus. [1] Effective birth control is recommended for both males and females for at least seven months during and after use. [8] The mechanism of action of ribavirin is not entirely clear. [1] Ribavirin was patented in 1971 and approved for medical use in 1986. [9]
Ribavirin: Hepatitis C [15] nucleoside analogue reverse transcriptase inhibitor: Rilpivirine (Edurant) [16] HIV Rimantadine: Influenza A: M2 proton channel antagonist Ritonavir: HIV HIV-1 protease inhibitor Saquinavir: HIV Simeprevir (Olysio) Hepatitis C Sofosbuvir: Hepatitis C [17] nucleoside analogue reverse transcriptase inhibitor: Stavudine ...
Gastrointestinal disturbances (including mouth ulcers, indigestion, diarrhea, constipation, etc.) Infections (including sinusitis, the flu, sepsis, UTIs, etc.)
During pregnancy when used with ribavirin it may cause harm to the baby while when used with sofosbuvir its safety is unclear. [2] [6] Simeprevir is a HCV protease inhibitor. [2] Simeprevir was developed by Medivir AB and Janssen Pharmaceutica. [7] It was approved for medical use in the United States in 2013. [8]
Estimated costs for a 12-week treatment of elbasvir/grazoprevir are upwards of $54,600. Other treatments that work in a similar manner have effectively more costs. Some treatments for Hepatitis C are on the cheaper side, in some instances as low as $8,400. Additional ribavirin costs can add between $500 and $900.
For each cup of heavy cream in a recipe, whisk together 2/3 cup soy milk and 1/3 cup oil. You can use olive oil or vegetable oil — it depends on the general flavor of the dish you plan to use it ...
If you’re out of shaving cream, we found five shaving cream substitutes that you can use instead. These quick solutions include baby oil, olive oil, and coconut oil.
In biochemistry, all reactions are simply theorized, with either weak , medium, or strong support. Saying "here are some posited mechanisms" is enough. You don't need to insert "We don't know the exact answer, and none of this has been proved" or similar statements because they are redundant. You can add such a statement to *any* scientific theory.
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