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The health effects associated with organophosphate poisoning are a result of excess acetylcholine (ACh) present at different nerve synapses and neuromuscular junctions across the body. Specifically, acetylcholinesterase (AChE), the enzyme that normally and constantly breaks down acetylcholine, is inhibited by the organophosphate substance.
A systematic review of neurodevelopmental effects of prenatal and postnatal organophosphate pesticide exposure was done in 2014. The review found that "Most of the studies evaluating prenatal exposure observed a negative effect on mental development and an increase in attention problems in preschool and school children." [30]
Reproductive toxicants may adversely affect sexual function, ovarian failure, fertility as well as causing developmental toxicity in the offspring. [ 2 ] [ 3 ] Lowered effective fertility related to reproductive toxicity relates to both male and female effects alike and is reflected in decreased sperm counts, semen quality and ovarian failure.
Nearly 50 years of research links two common insecticides used in food, yards and households to dramatically lower sperm count in men worldwide, a new study found.
TDCPP and other similar organophosphate flame retardants have been found to disrupt normal development. Chickens exposed to TDCPP as embryos developed abnormally: Exposure to 45 ug/g resulted in shorter head-to-bill lengths, decreased body weight, and smaller gallbladders, while 7.64 ug/g lowered free thyroxine (T4) levels in the blood. [30]
Health effects of pesticides may be acute or delayed in those who are exposed. [1] Acute effects can include pesticide poisoning, which may be a medical emergency. [2] Strong evidence exists for other, long-term negative health outcomes from pesticide exposure including birth defects, fetal death, [3] neurodevelopmental disorder, [4] cancer, and neurologic illness including Parkinson's disease ...
General chemical structure of the organophosphate functional group. In organic chemistry, organophosphates (also known as phosphate esters, or OPEs) are a class of organophosphorus compounds with the general structure O=P(OR) 3, a central phosphate molecule with alkyl or aromatic substituents. [1] They can be considered as esters of phosphoric ...
Here's why: The body uses nutrients from food to control different organ systems, including the endocrine system, which is in charge of making and regulating hormones like testosterone. Food can ...