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Nitrilotriacetic acid (NTA) is the aminopolycarboxylic acid with the formula N(CH 2 CO 2 H) 3. It is a colourless solid. It is a colourless solid. Its conjugate base nitrilotriacetate is used as a chelating agent for Ca 2+ , Co 2+ , Cu 2+ , and Fe 3+ .
.alpha.,.alpha.',.alpha.''-Trimethylaminetricarboxylic acid 2,2',2''-Nitrilotriacetic acid Acetic acid, nitrilotri- (8CI) alpha,alpha',alpha''-Trimethylaminetricarboxylic acid alpha,alpha',alpha''-trimethylaminetricarboxylic acid aminotriacetic acid Aminotriacetic acid Chel 300 chel 300 Complexon I Complexone I(R) Glycine, N,N-bis(carboxymethyl)- (9CI) hampshire nta acid Hampshire NTA acid ...
Nitrilotriacetonitrile reacts with methanal at pH 9.5 to give 2,2-dihydroxymethyl-nitrilotriacetonitrile, which is hydrolyzed with sodium hydroxide solution at 100 °C to give the trisodium salt of 2-hydroxymethylserine-N,N-diacetic acid, from which the free acid can be obtained by acidification in 51% yield.
An aminopolycarboxylic acid (sometimes abbreviated APCA) is a chemical compound containing one or more nitrogen atoms connected through carbon atoms to two or more carboxyl groups. Aminopolycarboxylates that have lost acidic protons form strong complexes with metal ions.
Realization of continuous process options; Achieving the lowest possible levels of impurities, particularly nitrilotriacetic acid, which is suspected of being carcinogenic; Use of inexpensive raw materials, e.g. instead of pure L-alanine the raw mixture of Strecker synthesis from methanal, hydrogen cyanide and ammonia
diethylenetriamineacetic acid DTMA [1] NH 2 C 2 H 4 NHC 2 H 4 NHCH 2 COOH linear NNNO 1– Co iso-diethylenetriamineacetic acid i-DTMA [1] (NH 2 C 2 H 4) 2 NCH 2 COOH tripodal N N 2NO 1– Co Jäger's N2O2 ligand linear acacen ONNO N 2 O 2: Ni Naphthalocyanine: C 48 H 26 N 8: ring NNNN 714.79 Nitrilotriacetic acid: NTA N(CH 2 CO 2 H) 3 ...
Various carrier matrices bound to a solid resin support are on the market and these can be subsequently charged with a metal cation. Derivatives of iminodiacetic acid (IDA) and nitrilotriacetic acid (NTA) are most frequently used for this purpose, with differing matrices having certain advantages and disadvantages for various applications. [14]
As biodegradable alternatives from the class of widespread chelating agents, only nitrilotriacetic acid (NTA) is sufficiently biodegradable under certain conditions (which is suspected of being carcinogenic, though) and the chelating active amino acid derivatives β-alaninediacetic acid and methylglycine diacetic acid (Trilon M®).