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Feet of a baby born to a mother who had taken thalidomide while pregnant. In the late 1950s and early 1960s, the use of thalidomide in 46 countries was prescribed to women who were pregnant or who subsequently became pregnant, and consequently resulted in the "biggest anthropogenic medical disaster ever," with more than 10,000 children born with a range of severe deformities, such as ...
Thousands of pregnant women took the drug to relieve their symptoms. At the time of the drug's development, scientists did not believe any drug taken by a pregnant woman could pass across the placental barrier and harm the developing fetus. [48] There soon appeared reports of abnormalities in children being born to mothers using thalidomide.
The pregnancy category of a medication is an assessment of ... are widely known to cause serious hazards to pregnant women and ... Previously approved drugs from June ...
The suppression of contractions is often only partial and tocolytics can only be relied on to delay birth for a matter of days. Depending on the tocolytic used, the pregnant woman or fetus may require monitoring (e.g., blood pressure monitoring when nifedipine is used as it reduces blood pressure; cardiotocography to assess fetal well-being ...
This is a complete list of estrogens and formulations that are approved by the FDA Tooltip Food and Drug Administration and available in the United States. Estrogens are used as hormonal contraceptives , in hormone replacement therapy , and in the treatment of gynecological disorders .
Mifepristone is approved in only one sub-Saharan African country—South Africa, where it was approved in 2001. [149] It is also approved in one north African country—Tunisia, also in 2001. [150] Mifepristone was approved for use in India in 2002, where medication abortion is referred to as "medical termination of pregnancy".
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