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The predominant cause of nutritional optic neuropathy is thought to be deficiency of B-complex vitamins, particularly thiamine [2] (vitamin B 1), cyanocobalamin (vitamin B 12) and recently copper. [3] Deficiency of pyridoxine (vitamin B 6), niacin (vitamin B 3), riboflavin (vitamin B 2), and/or folic acid also seems to play a role. Those ...
A major cause of Bitot's spots is vitamin A deficiency (VAD). [4] Rarely, pellagra due to deficiency of vitamin B 3 (niacin) may also cause Bitot's spots. [5] They can also be caused by Colestyramine , which is a bile acid sequestrant which can reduce the absorption of fat soluble vitamins (Vitamins A, D, E, K)
Keratomalacia is an eye disorder that results from vitamin A deficiency. Vitamin A is required to maintain specialized epithelia (such as in the cornea and conjunctiva ). The precise mechanism is still not known, but vitamin A is necessary for the maintenance of the specialized epithelial surfaces of the body.
Although synthetic vitamin A supplementation is a useful and effective treatment for VAD, a 2017 review (updated in 2022) reported that synthetic vitamin A supplementation may not be the best longāterm solution for vitamin A deficiency, but rather food fortification, improved food distribution programs, and crop improvement, such as for ...
It may be caused by vitamin A deficiency, [1] which is sometimes used to describe that condition, although there may be other causes. Xerophthalmia caused by a severe vitamin A deficiency is described by pathologic dryness of the conjunctiva and cornea. The conjunctiva becomes dry, thick and wrinkled. The first symptom is poor vision at night.
Vitamin A deficiency may also cause color blindness. [47] Color blindness may be a side effect of prescription drug use. For example, red–green color blindness can be caused by ethambutol, a drug used in the treatment of tuberculosis. [48] Blue–yellow color blindness can be caused by sildenafil, an active component of Viagra. [49]
Vitamin deficiency is the condition of a long-term lack of a vitamin. When caused by not enough vitamin intake it is classified as a primary deficiency, whereas when due to an underlying disorder such as malabsorption it is called a secondary deficiency. An underlying disorder can have 2 main causes:
UNICEF regards addressing vitamin A deficiency as critical to reducing child mortality, the fourth of the United Nations' Millennium Development Goals. [10] During diagnosis, night blindness and dry eyes are signs of vitamin A deficiency that can be recognized without requiring biochemical tests. Plasma retinol is used to confirm vitamin A status.