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For most people, recommendations are to reduce blood pressure to less than or equal to somewhere between 140/90 mmHg and 160/100 mmHg. [2] In general, for people with elevated blood pressure, attempting to achieve lower levels of blood pressure than the recommended 140/90 mmHg will create more harm than benefits, [3] in particular for older people. [4]
Blood pressure targets [7] <1 hr 25% reduction in the mean arterial pressure, diastolic blood pressure above 100 2-6 hr Systolic BP < 160 mmHg or Diastolic BP <110 mmHg 6-24 hr monitor BP targets, ensure non-rapid drop in BPs below 160 SBP or 100 DBP 1-2 d if no end-organ damage, monitor out-patient and JNC8 Guidelines for maintaining BP control
Chlorthalidone is the thiazide drug that is most strongly supported by the evidence as providing a mortality benefit; in the ALLHAT study, a chlorthalidone dose of 12.5 mg was used, with titration up to 25 mg for those subjects who did not achieve blood pressure control at 12.5 mg. Chlorthalidone has repeatedly been found to have a stronger ...
In contrast there is no evidence that blood pressure needs to be lowered rapidly in hypertensive urgencies, where there is no evidence of target organ damage; over-aggressive reduction of blood pressure is not without risks. [3] Use of oral medications to lower the BP gradually over 24 to 48h is advocated in hypertensive urgencies. [4]
Multiple blood pressure readings (at least two) spaced 1–2 minutes apart should be obtained to ensure accuracy. [92] Ambulatory blood pressure monitoring over 12 to 24 hours is the most accurate method to confirm the diagnosis. [93] An exception to this is those with very high blood pressure readings especially when there is poor organ ...
Atenolol is a beta blocker medication primarily used to treat high blood pressure and heart-associated chest pain. [7] Although used to treat high blood pressure, it does not seem to improve mortality in those with the condition. [8] [9] Other uses include the prevention of migraines and treatment of certain irregular heart beats.
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Reserpine is a drug that is used for the treatment of high blood pressure, usually in combination with a thiazide diuretic or vasodilator. [1] Large clinical trials have shown that combined treatment with reserpine plus a thiazide diuretic reduces mortality of people with hypertension.
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