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  2. Directionality (molecular biology) - Wikipedia

    en.wikipedia.org/wiki/Directionality_(molecular...

    The 3′-end (three prime end) of a strand is so named due to it terminating at the hydroxyl group of the third carbon in the sugar-ring, and is known as the tail end. The 3′-hydroxyl is necessary in the synthesis of new nucleic acid molecules as it is ligated (joined) to the 5′-phosphate of a separate nucleotide, allowing the formation of ...

  3. Sticky and blunt ends - Wikipedia

    en.wikipedia.org/wiki/Sticky_and_blunt_ends

    A single-stranded non-circular DNA molecule has two non-identical ends, the 3' end and the 5' end (usually pronounced "three prime end" and "five prime end"). The numbers refer to the numbering of carbon atoms in the deoxyribose, which is a sugar forming an important part of the backbone of the DNA molecule. In the backbone of DNA the 5' carbon ...

  4. Glossary of cellular and molecular biology (0–L) - Wikipedia

    en.wikipedia.org/wiki/Glossary_of_cellular_and...

    3' untranslated region (3'-UTR). Also three-prime untranslated region, 3' non-translated region (3'-NTR), and trailer sequence.. 3'-end. Also three-prime end.. One of two ends of a single linear strand of DNA or RNA, specifically the end at which the chain of nucleotides terminates at the third carbon atom in the furanose ring of deoxyribose or ribose (i.e. the terminus at which the 3' carbon ...

  5. Three prime untranslated region - Wikipedia

    en.wikipedia.org/wiki/Three_prime_untranslated...

    (See Central dogma of molecular biology). mRNA structure, approximately to scale for a human mRNA, where the median length of 3′UTR is 700 nucleotides. In molecular genetics, the three prime untranslated region (3′-UTR) is the section of messenger RNA (mRNA) that immediately follows the translation termination codon.

  6. DNA replication - Wikipedia

    en.wikipedia.org/wiki/DNA_replication

    DNA strands have a directionality, and the different ends of a single strand are called the "3′ (three-prime) end" and the "5′ (five-prime) end". By convention, if the base sequence of a single strand of DNA is given, the left end of the sequence is the 5′ end, while the right end of the sequence is the 3end.

  7. Untranslated region - Wikipedia

    en.wikipedia.org/wiki/Untranslated_region

    The 3' UTR varies in length as well. The poly-A tail is essential for keeping the mRNA from being degraded. Although there is variation in lengths of both the 5' and 3' UTR, it has been seen that the 5' UTR length is more highly conserved in evolution than the 3' UTR length. [5]

  8. Reading frame - Wikipedia

    en.wikipedia.org/wiki/Reading_frame

    A single strand of a nucleic acid molecule has a phosphoryl end, called the 5′-end, and a hydroxyl or 3′-end. These define the 5′→3′ direction. There are three reading frames that can be read in this 5′→3′ direction, each beginning from a different nucleotide in a triplet.

  9. Prime end - Wikipedia

    en.wikipedia.org/wiki/Prime_end

    The set of prime ends of the domain B is the set of equivalence classes of chains of arcs converging to a point on the boundary of B. In this way, a point in the boundary may correspond to many points in the prime ends of B, and conversely, many points in the boundary may correspond to a point in the prime ends of B. [3]