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When salt is ingested, it's dissolved in the blood as two separate ions – Na + and Cl −. The water potential in blood will decrease due to the increased solutes, and blood osmotic pressure will increase. While the kidney reacts to excrete excess sodium and chloride in the body, water retention causes blood pressure to increase. [10]
The salt substitute used was 25% potassium chloride and 75% sodium chloride. A 2022 Cochrane review of 26 trials involving salt substitutes reported their use probably slightly reduces blood pressure, non-fatal stroke, non-fatal acute coronary syndrome and heart disease death in adults compared to use of regular table salt. [9]
Reduced salt intake also results in a small but statistically significant reduction in blood pressure. [19] [26] Left ventricular hypertrophy (cardiac enlargement): "Evidence suggests that high salt intake causes left ventricular hypertrophy. This is a strong risk factor for cardiovascular disease, independently of blood pressure effects."
A low sodium diet has a useful effect to reduce blood pressure, both in people with hypertension and in people with normal blood pressure. [7] Taken together, a low salt diet (median of approximately 4.4 g/day – approx 1800 mg sodium) in hypertensive people resulted in a decrease in systolic blood pressure by 4.2 mmHg, and in diastolic blood pressure by 2.1 mmHg.
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However, if diagnosed with Pheochromocytoma, there will be a neuroendocrine tumour that is found in the adrenal gland which can cause overproduction of induced hormones that can lead to episodic of high blood pressure. [8] Salt: People may develop blood pressure spikes in high sodium intake that is contained in meals. High sodium intake may put ...
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