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  2. Autoimmune skin diseases in dogs - Wikipedia

    en.wikipedia.org/wiki/Autoimmune_skin_diseases...

    Many forms of pemphigus can be identified in dogs using methods similar to those employed for humans. [14] Pemphigus vulgaris is rare in humans and animals, but is often fatal if left untreated. In dogs, the disease presents itself so similarly to the way it occurs in humans that dogs can be used as models for the disease in humans. [4]

  3. List of immunofluorescence findings for autoimmune bullous ...

    en.wikipedia.org/wiki/List_of_immunofluorescence...

    Substrates used in indirect immunofluorescence studies for the different pemphigus variants Pemphigus variant Substrate Pemphigus foliaceous: Guinea pig esophagus Pemphigus vulgaris: Monkey esophagus IgA pemphigus: Cultured skin Paraneoplastic pemphigus: Rat bladder

  4. Paraneoplastic pemphigus - Wikipedia

    en.wikipedia.org/wiki/Paraneoplastic_pemphigus

    Paraneoplastic pemphigus (PNP) is an autoimmune disorder stemming from an underlying tumor. It is hypothesized that antigens associated with the tumor trigger an immune response resulting in blistering of the skin and mucous membranes .

  5. Paraneoplastic syndrome - Wikipedia

    en.wikipedia.org/wiki/Paraneoplastic_syndrome

    Symptomatic features of paraneoplastic syndrome cultivate in four ways: endocrine, neurological, mucocutaneous, and hematological.The most common presentation is a fever (release of endogenous pyrogens often related to lymphokines or tissue pyrogens), but the overall picture will often include several clinical cases observed which may specifically simulate more common benign conditions.

  6. List of target antigens in pemphigus - Wikipedia

    en.wikipedia.org/wiki/List_of_target_antigens_in...

    Pemphigus foliaceus: IgG: Desmoglein 1: 160 Paraneoplastic pemphigus: IgG: Desmoglein 3 Desmoglein 1 BPAG1 [nb 1] Plectin Desmoplakin I [nb 2] Desmoplakin II Envoplakin Periplakin Alpha-2-macroglobulin-like-1: 130 160 230 500 250 210 210 190 170 Drug-induced pemphigus: IgG: Desmoglein 3 Desmoglein 1: 130 160 Subcorneal pustular dermatosis type ...

  7. Bullous pemphigoid - Wikipedia

    en.wikipedia.org/wiki/Bullous_pemphigoid

    Very rarely seen in children, bullous and non-bullous pemphigoid most commonly occurs in people 70 years of age and older. [2] Its estimated frequency is seven to 14 cases per million per year, but has been reported to be as high as 472 cases per million per year in Scottish men older than 85. [2]

  8. Pemphigus - Wikipedia

    en.wikipedia.org/wiki/Pemphigus

    Pemphigus is further divided in two major subtypes: pemphigus vulgaris (PV) and pemphigus foliaceus (PF). However, several other disorders such as IgA pemphigus, IgE pemphigus, pemphigus herpetiformis, drug-induced pemphigus, Senear Usher syndrome, and endemic pemphigus foliaceus exist, and are recognized by a dermatologist from the appearance ...

  9. Mucous membrane pemphigoid - Wikipedia

    en.wikipedia.org/wiki/Mucous_membrane_pemphigoid

    If no lesions are present on examination it may be useful way of demonstrating reduced epithelial adhesion. In contrast, in Pemphigus, the epithelium tends to disintegrate rather than form a bulla. Nikolsky's sign is present in pemphigus and mucous membrane pemphigoid, but not in bullous pemphigoid.