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Selenomethionine is readily available as a dietary supplement. It has been suggested by nutritionists that selenomethionine, as an organic form of selenium, is easier for the human body to absorb than selenite, which is an inorganic form. [8] It was determined in a clinical trial that selenomethionine is absorbed 19% better than selenite. [8]
For example, selenomethionine and selenocysteine are selenium-containing amino acids present in the human body. Selenomethionine participates in the synthesis of selenoproteins . [ 2 ] The reduction potential and pKa (5.47) of selenocysteine are lower than those of cysteine , making some proteins have antioxidant activity. [ 3 ]
The ingredient is also used in body lotions to treat Tinea versicolor due to infection by a different species of Malassezia fungus. [12] Several clinical trials have assessed the use of selenium supplements in critically ill adults; however, the effectiveness and potential benefits of selenium supplementation in this context is not well ...
The Food and Drug Administration (FDA) recently approved the nasal spray Spravato for the treatment of major depression in people who have not responded to at least two oral antidepressants.
Methaneselenol (commonly named "methylselenol") (CH 3 SeH), which can be produced in vitro by incubating selenomethionine with a bacterial methionine gamma-lyase (METase) enzyme, by biological methylation of selenide ion or in vivo by reduction of methaneseleninic acid (CH 3 −Se(=O)−OH), has been invoked to explain the anticancer activity ...
Selenoneine is a selenium containing ergothioneine derivative where the selenium (Se) atom replaces a sulfur atom. It can be systematically named as (2-selenyl-N α,N α,N α-trimethyl-L-histidine or 3-(2-hydroseleno-1H-imidazol-5-yl)-2-(trimethylammonio)propanoate).
Organoselenium compounds are required for cellular defense against oxidative damage and for the correct functioning of the immune system. They may also play a role in prevention of premature aging and cancer. The source of Se used in biosynthesis is selenophosphate. Glutathione oxidase is an enzyme with a selenol at its active site ...
The chief commercial uses for selenium today are glassmaking and pigments. Selenium is a semiconductor and is used in photocells. Applications in electronics, once important, have been mostly replaced with silicon semiconductor devices. Selenium is still used in a few types of DC power surge protectors and one type of fluorescent quantum dot.
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