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The gene for LAMP2 has 9 coding exons and 2 alternate last exons, 9a and 9b. [6] When the last exon is spliced with the alternative exon, it is a variant called LAMP2b, which varies in the last 11 amino acids of its C-terminal sequence: in the luminal domain, the transmembrane domain, and the cytoplasmic tail.
A light combat aircraft (LCA) is a light, multirole jet/turboprop military aircraft, commonly derived from advanced trainer designs, designed for engaging in light combat. [ citation needed ] The mission can either be in a light strike or attack missions , reconnaissance , interdiction roles or trainer roles and even air-to-air fight.
Structurally, the lamp proteins consist of two internally homologous lysosome-luminal domains separated by a proline-rich hinge region; at the C-terminal extremity there is a transmembrane region (TM) followed by a very short cytoplasmic tail (C). In each of the duplicated domains, there are two conserved disulfide bonds. This structure is ...
HAL Tejas This is a timeline of the development of the HAL Tejas, a light-weight, multirole fighter aircraft manufactured by Hindustan Aeronautics Limited. 1980s 1983 The DRDO obtains permission to initiate a programme to design and develop a light combat aircraft. 1984 Government of India set up Aeronautical Development Agency (ADA) in 1984 as the nodal agency for managing and developing the ...
Leber congenital amaurosis (LCA) is a rare inherited eye disease that appears at birth or in the first few months of life. [2]It affects about 1 in 40,000 newborns. [1] LCA was first described by Theodor Leber in the 19th century.
For the LCA programme, the GTRE would again take up a turbofan design which it designated the GTX-35VS "Kaveri" (named after the Kaveri River). Full-scale development was authorized in April 1989 in what was then expected to be a 93-month programme projected to cost ₹ 382.21 crore (equivalent to ₹ 41 billion or US$470 million in 2023). The ...
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