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Inbreeding is the production of offspring from the mating or breeding of individuals or organisms that are closely related genetically. [1] By analogy, the term is used in human reproduction , but more commonly refers to the genetic disorders and other consequences that may arise from expression of deleterious recessive traits resulting from ...
The hypothesis states that inbreeding increases the amount of overall homozygosity—not just locally in the MHC, so an increase in genetic homozygosity may be accompanied not only by the expression of recessive diseases and mutations, but by the loss of any potential heterozygote advantage as well. [17] [2] Animals only rarely avoid inbreeding ...
A diploid organism is heterozygous at a gene locus when its cells contain two different alleles (one wild-type allele and one mutant allele) of a gene. [3] The cell or organism is called a heterozygote specifically for the allele in question, and therefore, heterozygosity refers to a specific genotype. Heterozygous genotypes are represented by ...
Genetic purging is the increased pressure of natural selection against deleterious alleles prompted by inbreeding. [1]Purging occurs because deleterious alleles tend to be recessive, which means that they only express all their harmful effects when they are present in the two copies of the individual (i.e., in homozygosis).
Though there are many traits about zebrafish that are worthwhile to study including their regeneration, there are relatively few inbred strains of zebrafish possibly because they experience greater effects from inbreeding depression than mice or Medaka fish, but it is unclear if the effects of inbreeding can be overcome so an isogenic strain ...
Partial penetrance can be shown and calculated from pedigrees. Penetrance is the percentage expressed frequency with which individuals of a given genotype manifest at least some degree of a specific mutant phenotype associated with a trait. Inbreeding, or mating between closely related organisms, can clearly be seen on pedigree charts. Pedigree ...
As opposed to outcrossing or outbreeding, inbreeding is the process by which organisms with common descent come together to mate and eventually procreate. [4] An archetype of inbreeding is self-pollination. When a plant has both anthers and a stigma, the process of inbreeding can occur.
A common cause of non-random mating is inbreeding, which causes an increase in homozygosity for all genes. If a population violates one of the following four assumptions, the population may continue to have Hardy–Weinberg proportions each generation, but the allele frequencies will change over time.