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The absorbed dose can be a poor indicator of the biological effect of radiation, as the biological effect can depend on many other factors, including the type of radiation, energy, and type of tissue. The relative biological effectiveness can help give a better measure of the biological effect of radiation.
The radiation weighting conversion factor from absorbed dose to equivalent dose is 1 for gamma, whereas alpha particles have a factor of 20, reflecting their greater ionising effect on tissue. The rad is the deprecated CGS unit for absorbed dose and the rem is the deprecated CGS unit of equivalent dose, used mainly in the USA.
The effects of radiation on cells has been found to be dependent on the dosage of the radiation, the location of the cell in regards to tissue, and whether the cell is a somatic or germ line cell. Generally, ionizing radiation appears to reduce methylation of DNA in cells. [1]
Radiobiology is the study of the action of ionizing radiation on living things, including the health effects of radiation in humans. High doses of ionizing radiation can cause damage to living tissue such as radiation burning and harmful mutations such as causing cells to become cancerous, and can lead to health problems such as radiation ...
deterministic effects (harmful tissue reactions) due in large part to killing or malfunction of cells following high doses from radiation burns. stochastic effects, i.e., cancer and heritable effects involving either cancer development in exposed individuals owing to mutation of somatic cells or heritable disease in their offspring owing to ...
Nevertheless, the effects of low doses are mostly unknown so many regulations exist to avoid unnecessary risks, such as skin or internal exposure. Due to the low penetration power and many variables involved it is hard to convert a radioactive concentration to a dose. 1 μCi of P-32 on a square centimetre of skin (through a dead layer of a ...
Tumor cells can be hypoxic and therefore less sensitive to X-rays because most of their effects are mediated by the free radicals produced by ionizing oxygen. It has meanwhile been shown that the most sensitive cells are those that are undifferentiated , well nourished, dividing quickly and highly active metabolically .
deterministic effects (harmful tissue reactions) due in large part to the killing or malfunction of cells following high doses; and stochastic effects, i.e., cancer and heritable effects involving either cancer development in exposed individuals owing to mutation of somatic cells or heritable disease in their offspring owing to mutation of ...