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Due to the risks of certain side effects of the drug, including abuse and misuse, a person must administer the nasal spray in a clinic or doctor’s office under medical supervision. Alternative ...
Esketamine, sold under the brand names Spravato (for depression) and Ketanest (for anesthesia) among others, [10] [12] is the S(+) enantiomer of ketamine. [5] [13] It is a dissociative hallucinogen drug used as a general anesthetic and as an antidepressant for treatment of depression.
Lighter Side. Politics. Science & Tech. Sports. Weather. ... the ketamine-derived nasal spray sold under the brand name Spravato (esketamine), is indicated for patients with treatment-resistant ...
The nasal spray was first approved by the FDA in 2019 as a supplemental treatment, along with an oral medication, for the approximately one-third of people with MDD who struggle with treatment ...
Since 2010, ketamine has been prescribed off-label to patients with severe depression with the informed consent of patients. [26] In 2019, the FDA approved the use of esketamine (Spravato) as a nasal spray, in conjunction with an oral antidepressant, for treatment-resistant depression in adults.
Ketamine potentiates the sedative effects of propofol [86] and midazolam. [87] Naltrexone potentiates psychotomimetic effects of a low dose of ketamine, [88] while lamotrigine [38] and nimodipine [39] decrease them. Clonidine reduces the increase of salivation, heart rate, and blood pressure during ketamine anesthesia and decreases the ...
The U.S. Food and Drug Administration expanded approval for Johnson & Johnson’s nasal spray, ... Lighter Side. Politics. Science & Tech ... The ketamine-derived drug was first approved in 2019 ...
Narcan nasal spray is intended for distribution to the general public, [15] allowing the friends or family of an overdose victim to counteract the drug's effects almost immediately, without waiting for emergency response personnel to arrive. Many lives are lost due to drug users' hesitance to contact emergency services, a trend which Narcan ...
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