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Melatonin may be useful in the treatment of delayed sleep phase syndrome. [9] Melatonin is known to reduce jet lag, especially in eastward travel. However, if it is not taken at the correct time, it can instead delay adaptation. [30] Melatonin appears to have limited use against the sleep problems of people who work shift work. [31]
Melatonin supplements for sleep come with side effects and their use may raise safety concerns, experts say. There's little evidence they help with insomnia.
Prolonged-release melatonin may improve the quality of sleep in older people with minimal side effects. [166] [167] Studies have also shown that children who are on the autism spectrum or have learning disabilities, attention-deficit hyperactivity disorder (ADHD) or related neurological diseases can benefit from the use of melatonin. This is ...
Melatonin, an indoleamine, is a natural compound produced by various organisms, including bacteria and eukaryotes. [1] Its discovery in 1958 by Aaron B. Lerner and colleagues stemmed from the isolation of a substance from the pineal gland of cows that could induce skin lightening in common frogs.
“Melatonin is typically touted to promote sleep onset, while magnesium may be better for maintaining sleep throughout the night,” he says. How often a person plans to take the sleep supplement ...
This is how melatonin helps regulate our circadian rhythm, which is our biological 24-hour clock,” Dr. Dasgupta says, adding that we sleep best when melatonin is secreted appropriately.
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