Ad
related to: what is guanidine used for in plants and humansgoodrx.com has been visited by 100K+ users in the past month
- Our Social Impact Mission
At GoodRx, values matter. Visit us
to see how we make a difference.
- GoodRx® & Medicare
Beat your Medicare Copay!
Discover More Savings Options Today
- GoodRx® Press
"Shop wisely with GoodRx"
Featured on CNN & Forbes.
- Research You Can Rely On
Our team works hard to provide you
with the latest healthcare info.
- Our Social Impact Mission
Search results
Results from the WOW.Com Content Network
Guanidine exists protonated, as guanidinium, in solution at physiological pH. Guanidinium chloride (also known as guanidine hydrochloride) has chaotropic properties and is used to denature proteins. Guanidinium chloride is known to denature proteins with a linear relationship between concentration and free energy of unfolding.
It is also used in metallic paints and simulated pearls and plastics. It provides shimmering luster to eye shadow and nail polish . Facial treatments using the droppings, or guano, from Japanese nightingales have been used in Japan and elsewhere, because the guanine in the droppings makes the skin look paler. [ 10 ]
Guanidinium thiocyanate can be used to deactivate a virus, such as the influenza virus that caused the 1918 "Spanish flu", so that it can be studied safely.. Guanidinium thiocyanate is also used to lyse cells and virus particles in RNA and DNA extractions, where its function, in addition to its lysing action, is to prevent activity of RNase enzymes and DNase enzymes by denaturing them.
In the 1920s, guanidine compounds were discovered in Galega extracts. Animal studies showed that these compounds lowered blood glucose levels. Some less toxic derivatives, synthalin A and synthalin B, were used for diabetes treatment, but after the discovery of insulin, their use declined.
Tetramethylguanidine is mainly used as a strong, non-nucleophilic base for alkylations, often as a substitute for the more expensive DBU and DBN. [3] Since it is highly water-soluble, it is easily removed from mixtures in organic solvents. It is also used as a base-catalyst in the production of polyurethane. [4]
Guanidinium chloride is a weak acid with a pK a of 13.6. The reason that it is such a weak acid is the complete delocalization of the positive charge through three nitrogen atoms (plus a little bit of positive charge on carbon).
For premium support please call: 800-290-4726 more ways to reach us
Galegine was used in the 1920s as a pharmaceutical treatment for diabetes; [3] however, because of its toxicity, its use was soon supplanted by superior alternatives. Research on galegine eventually led to the development of metformin which is used today for treatment of type 2 diabetes .
Ad
related to: what is guanidine used for in plants and humansgoodrx.com has been visited by 100K+ users in the past month