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  2. Pathophysiology of multiple sclerosis - Wikipedia

    en.wikipedia.org/wiki/Pathophysiology_of...

    Myelin sheath damage in multiple sclerosis. Multiple sclerosis can be pathologically defined as the presence of distributed glial scars (or sclerosis) in the central nervous system disseminated in time (DIT) and space (DIS). [2] The gold standard for MS diagnosis is pathological correlation, though given its limited availability, other ...

  3. Inflammatory demyelinating diseases of the central nervous ...

    en.wikipedia.org/wiki/Inflammatory_demyelinating...

    Inflammatory demyelinating diseases (IDDs), sometimes called Idiopathic (IIDDs) due to the unknown etiology of some of them, are a heterogenous group of demyelinating diseases - conditions that cause damage to myelin, the protective sheath of nerve fibers - that occur against the background of an acute or chronic inflammatory process.

  4. Pathology of multiple sclerosis - Wikipedia

    en.wikipedia.org/.../Pathology_of_multiple_sclerosis

    It also seems that myelin basic protein (MBP) from multiple sclerosis (MS) patients contains lower levels of phosphorylation at Thr97 than normal individuals. [152] NAWM is the place where lesions appear and the process seems to be made by microglia, in absence of leukocyte infiltration, astrogliosis or demyelination.

  5. New treatment may stop and potentially reverse some nerve ...

    www.aol.com/treatment-may-stop-potentially...

    A new study has developed a treatment that can help regenerate myelin with the potential to stop and even heal the damage caused by MS. Multiple sclerosis (MS) is an autoimmune disorder in which ...

  6. Multiple sclerosis - Wikipedia

    en.wikipedia.org/wiki/Multiple_sclerosis

    Multiple sclerosis (MS) is an autoimmune disease resulting in damage to the insulating covers of nerve cells in the brain and spinal cord. [3] As a demyelinating disease , MS disrupts the nervous system's ability to transmit signals , resulting in a range of signs and symptoms , including physical, mental , and sometimes psychiatric problems.

  7. Is Multiple Sclerosis an Autoimmune Disease? We Asked ... - AOL

    www.aol.com/multiple-sclerosis-autoimmune...

    Doctors debate whether MS is an autoimmune disorder, arguing that it could possibly be a neurodegenerative disorder instead. Scientists have also made headway into several cause-related theories.

  8. Lesional demyelinations of the central nervous system

    en.wikipedia.org/wiki/Lesional_demyelinations_of...

    Often, the brain is able to compensate for some of this damage, due to an ability called neuroplasticity. MS symptoms develop as the cumulative result of multiple lesions in the brain and spinal cord. This is why symptoms can vary greatly between different individuals, depending on where their lesions occur.

  9. Diagnosis of multiple sclerosis - Wikipedia

    en.wikipedia.org/.../Diagnosis_of_multiple_sclerosis

    Multiple sclerosis diagnosis can only be made when there is proof of lesions disseminated in time and in space. Therefore, when damage in the CNS is big enough to be seen. It would be desirable to make it faster. The ideal diagnosis schema would be able to determine for any given subject, if he will develop MS, at any point in his life, and when.

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