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www.schrodinger.com /products /glide Glide is a molecular modeling software for docking of small molecules into proteins and other biopolymers . [ 1 ] [ 2 ] It was developed by Schrödinger, Inc.
Unlike previous docking systems, either APAS-75 unit could assume the active or passive role as required. For docking, the spade-shaped guides of the extended active unit (right) and the retracted passive unit (left) interacted for gross alignment. The ring holding the guides shifted to align the active unit latches with the passive unit catches.
During the course of the docking process, the ligand and the protein adjust their conformation to achieve an overall "best-fit" and this kind of conformational adjustment resulting in the overall binding is referred to as "induced-fit". [5] Molecular docking research focuses on computationally simulating the molecular recognition process.
Lloyd, Alwyn T. (2000), A Cold War Legacy, A Tribute to Strategic Air Command, 1946–1992, Pictorial Histories Publications ISBN 1-57510-052-5; Rogers, Brian (2005). United States Air Force Unit Designations Since 1978. Hinkley, England: Midland Publications. ISBN 1-85780-197-0.
During the 1950s and 1960s Both the United States and the Soviet Union developed nuclear weapons small enough to be portable in specially-designed backpacks. [1] [2] Neither the United States nor the Soviet Union have ever made public the existence or development of weapons small enough to fit into a normal-sized suitcase or briefcase. [3]
The Front-end Robotics Enabling Near-term Demonstration (FREND, a play on friend) is a DARPA project "aiming to create a fully autonomous docking capability for satellites that weren't built to be serviced", currently under testing at the U.S. Naval Research Laboratory Spacecraft Engineering Department.
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