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Ruxolitinib (sold under the brand names Jakafi and Jakavi among others, and as Opzelura in cream form) is a medication used for the treatment of intermediate or high-risk myelofibrosis, [6] a type of myeloproliferative neoplasm that affects the bone marrow; [11] [12] polycythemia vera, when there has been an inadequate response to or intolerance of hydroxyurea; [6] [13] and steroid-refractory ...
The prescribing information for Jakafi now includes a new recommended starting dose of 5 mg twice daily of Jakafi for patients with baseline platelet counts between 50-100 x 10 9 /L (50,000 to ...
Diagram of a submarine's baffles where its sonar is ineffective. The baffles is the area in the water directly behind a submarine or ship through which a hull-mounted sonar cannot hear. This blind spot is caused by the need to insulate the sonar array, commonly mounted near the bow, from the noise of the vessel's machinery.
In this case the baffle helps increase the efficiency of the stove as more heat leaves the gas before it exits. The baffles prevent the rotational flow without affecting radial or longitudinal flow. The tank is provided with baffles which prevent swirling and vortex formation. Except in very large tanks, four(4) baffles are placed.
The KiHa 35 series (キハ35), along with the similar KiHa 30 and KiHa 36 series, are Japanese diesel multiple unit (DMU) train types formerly operated by the Japanese National Railways (JNR) and JR Group of companies, and later operated by the private railway operators Kanto Railway and Mizushima Rinkai Railway. They were built from 1961 until ...
A number of variants were produced with different engine installations, resulting in a series of model designations. Roughly concurrently with the development of the Continental-powered CP-series, Porterfield also developed variants (under the same ATCs) to accommodate comparable Lycoming engines (LP-50, LP-55 and LP-65 -- over 400 built, in ...
The Pup was developed to appear in 1935 as the Porterfield Model 35 Flyabout a braced high-wing-monoplane. It had a fixed tailskid landing gear and room for two. It was originally powered by a 60 hp (45 kW) LeBlond 5D radial engine. Variants later appeared with different engine installations and a deluxe model the De Luxe Sport. Over 240 ...
The 10.5 cm hrubý kanón vz. 35 (Heavy Gun model 35) was a Czech field gun used in the Second World War. Those weapons captured after the German occupation of Czechoslovakia in March 1939 were taken into Wehrmacht service as the 10.5 cm K 35(t). Former Yugoslav guns were designated as the 10.5 cm Kanone 339(j).