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Lead exposure damages cells in the hippocampus, a part of the brain involved in memory. Hippocampi of lead-exposed rats (bottom) show structural damage such as irregular nuclei (IN) and denaturation of myelin (DMS) compared to controls (top). [201] The brain is the organ most sensitive to lead exposure. [77]
Lead metal has several useful mechanical properties, including high density, low melting point, ductility, and relative inertness. Many metals are superior to lead in some of these aspects but are generally less common and more difficult to extract from parent ores. Lead's toxicity has led to its phasing out for some uses. [215]
In the human brain the hippocampus, the dentate gyrus, and the subiculum are components of the hippocampal formation located in the limbic system. The hippocampus plays important roles in the consolidation of information from short-term memory to long-term memory , and in spatial memory that enables navigation .
The latest research looked at a part of the brain called the olfactory bulb, which processes information about smell. Humans have two olfactory bulbs, one above each nasal cavity. Humans have two ...
Some plaques occur in the brain as a result of aging, but large numbers of plaques and neurofibrillary tangles are characteristic features of Alzheimer's disease. [5] The plaques are highly variable in shape and size; in tissue sections immunostained for Aβ, they comprise a log-normal size distribution curve, with an average plaque area of 400 ...
The posterior cingulate cortex (PCC) is the caudal part of the cingulate cortex, located posterior to the anterior cingulate cortex. This is the upper part of the "limbic lobe". The cingulate cortex is made up of an area around the midline of the brain. Surrounding areas include the retrosplenial cortex and the precuneus.
"Lead can be damaging to the developing brain," Calello says. "While adults can have effects from excess lead exposure as well, the effects are more severe in children and occur at lower levels."
The cerebral cortex, also known as the cerebral mantle, [1] is the outer layer of neural tissue of the cerebrum of the brain in humans and other mammals.It is the largest site of neural integration in the central nervous system, [2] and plays a key role in attention, perception, awareness, thought, memory, language, and consciousness.