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Immunohistochemistry for CK7 of a metastatic undifferentiated carcinoma to a lymph node. Because the keratin-7 antigen is found in both healthy and neoplastic cells, antibodies to CK7 can be used in immunohistochemistry to distinguish ovarian and transitional cell carcinomas (staining positive) from colonic and prostate cancers (negative), respectively.
Expression of these cytokeratins is largely organ or tissue specific. The subsets of cytokeratins which an epithelial cell expresses depends mainly on the type of epithelium, the moment in the course of terminal differentiation and the stage of development. Thus a specific cytokeratin expression profile allows the identification of epithelial ...
A Toker cell is an epithelial cell with clear cytoplasm in the nipple of some women. [1] Toker cells are believed to develop from sebaceous glands. [1] They are cytokeratin 7 (CK7) positive, in contrast to squamous epithelium. [1]
2625 14462 Ensembl ENSG00000107485 ENSMUSG00000015619 UniProt P23771 P23772 RefSeq (mRNA) NM_001002295 NM_002051 NM_008091 NM_001355110 NM_001355111 NM_001355112 RefSeq (protein) NP_001002295 NP_002042 NP_032117 NP_001342039 NP_001342040 NP_001342041 Location (UCSC) Chr 10: 8.05 – 8.08 Mb Chr 2: 9.86 – 9.89 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse GATA3 is a transcription ...
18510 Ensembl ENSG00000125618 ENSMUSG00000026976 UniProt Q06710 Q00288 RefSeq (mRNA) NM_003466 NM_013951 NM_013952 NM_013953 NM_013992 NM_011040 RefSeq (protein) NP_003457 NP_039246 NP_039247 NP_054698 NP_035170 Location (UCSC) Chr 2: 113.22 – 113.28 Mb Chr 2: 24.31 – 24.37 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Paired box gene 8, also known as PAX8, is a protein which ...
Epigenetics of human development is the study of how epigenetics (hertiable characteristics that do not involve changes in DNA sequence) effects human development. Development before birth, including gametogenesis , embryogenesis , and fetal development , is the process of body development from the gametes are formed to eventually combine into ...
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Keratin 20, often abbreviated CK20, is a protein that in humans is encoded by the KRT20 gene. [5] [6] [7]Keratin 20 is a type I cytokeratin.It is a major cellular protein of mature enterocytes and goblet cells and is specifically found in the gastric and intestinal mucosa.