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John Calhoun (age 52) with mice experiment (1970). While Calhoun was working at the National Institute of Mental Health (NIMH) in 1954, he began numerous experiments with rats and mice. During his first tests, he placed around 32 to 56 rats in a 10-by-14-foot (3.0 m × 4.3 m) cage in a barn in Montgomery County .
It was here that his most famous experiment, the mouse universes (the most famous of which is universe 25), was created. [1] In July 1968, four pairs of mice were introduced into the habitat. The habitat was a 9-foot (2.7 m; 110 in; 270 cm) square metal pen with 4.5-foot-high (1.4 m; 54 in; 140 cm) sides.
They come to the aid of Mrs. Frisby, a widowed field mouse who seeks to protect her children and home from destruction by a farmer's plow. [5] The rats of NIMH were inspired by the research of John B. Calhoun on mouse and rat population dynamics at the National Institute of Mental Health from the 1940s to the 1960s. [6]
Calhoun's experiments on mouse and rat population dynamics inspired novelist Robert C. O'Brien to write Mrs. Frisby and the Rats of NIMH, a 1971 children's book about laboratory rats who escape from the institute and develop a literate and technological society. [26] The book was adapted for film in 1982 as The Secret of NIMH.
The Seduction Experiment involved four groups of 8 rats. [4] Group CC was isolated in laboratory cages when they were weaned at 22 days of age, and lived there until the experiment ended at 80 days of age; Group PP was housed in Rat Park for the same period; Group CP was moved from laboratory cages to Rat Park at 65 days of age; and Group PC ...
The Silver Spring monkeys were 17 wild-born macaque monkeys from the Philippines who were kept in the Institute for Behavioral Research in Silver Spring, Maryland. [2] From 1981 until 1991, they became what one writer called the most famous lab animals in history, as a result of a battle between animal researchers, animal advocates, politicians, and the courts over whether to use them in ...
John Caldwell Calhoun (/ k æ l ˈ h uː n /; [1] March 18, 1782 – March 31, 1850) was an American statesman and political theorist who served as the seventh vice president of the United States from 1825 to 1832.
The Utopia Experiment was an experiment by Dylan Evans, set up in 2006 at Netherton Farm, near Culbokie on the Black Isle peninsula in the Scottish highlands. [1] It involved a group of volunteers improvising a post-apocalyptic lifestyle .