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This category contains disorders of the muscular system This category reflects the organization of International Statistical Classification of Diseases and Related Health Problems, 10th Revision . Generally, diseases outlined within the ICD-10 codes M60-M63 within Chapter XIII: Diseases of the musculoskeletal system and connective tissue should ...
Limb girdle muscular dystrophies (LGMD) as defined by the European Neuromuscular Centre in 2018. [1] [2] They are named by the following system: LGMD, recessive or dominant inheritance (R or D), order of discovery (number), affected protein.
Muscular dystrophies are caused by mutations in genes, usually those involved in making muscle proteins. [2] The muscle protein, dystrophin, is in most muscle cells and works to strengthen the muscle fibers and protect them from injury as muscles contract and relax. [3] It links the muscle membrane to the thin muscular filaments within the cell.
Muscular dystrophies, including Duchenne's and Becker's, are a large group of diseases, many of them hereditary or resulting from genetic mutations, where the muscle integrity is disrupted, they lead to progressive loss of strength and decreased life span. [17] Further causes of neuromuscular diseases are: Polymyositis. Inflammatory muscle ...
There is a growing consensus that psychosocial factors are another cause of some MSDs. [11] Some theories for this causal relationship found by many researchers include increased muscle tension, increased blood and fluid pressure, reduction of growth functions, pain sensitivity reduction, pupil dilation, body remaining at heightened state of sensitivity.
Musculoskeletal injury spans into a large variety of medical specialties including orthopedic surgery (with diseases such as arthritis requiring surgery), sports medicine, [5] emergency medicine (acute presentations of joint and muscular pain) and rheumatology (in rheumatological diseases that affect joints such as rheumatoid arthritis).
Facioscapulohumeral muscular dystrophy (FSHD) is a type of muscular dystrophy, a group of heritable diseases that cause degeneration of muscle and progressive weakness. Per the name , FSHD tends to sequentially weaken the muscles of the face , those that position the scapula , and those overlying the humerus bone of the upper arm.
Spinal muscular atrophy (SMA) is a rare neuromuscular disorder that results in the loss of motor neurons and progressive muscle wasting. [ 3 ] [ 4 ] [ 5 ] It is usually diagnosed in infancy or early childhood and if left untreated it is the most common genetic cause of infant death. [ 6 ]