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Many drugs have been discovered to treat the disease but mutations in the virus and resistance to the drugs make development difficult. Integrase is a viral enzyme that integrates retroviral DNA into the host cell genome. Integrase inhibitors are a new class of drugs used in the treatment of HIV.
HIV vaccine development is an active area of research and an important tool for managing the global AIDS epidemic. Research into a vaccine for HIV has been ongoing for decades with no lasting success for preventing infection. [151] The rapid development, though, of mRNA vaccines to deal with the COVID-19 pandemic may provide a new path forward.
HIV infection was first described in 1981 in San Francisco and New York City. [7] In 1985, HIV was identified as the causative agent of acquired immune deficiency syndrome (AIDS) and its complete genome was immediately available. This knowledge paved the way for the development of selective inhibitors. [6]
GSK said on Monday a new formulation of its HIV prevention and treatment drug could potentially be administered at least every four months, an improvement from the previous requirement of dosing ...
At the HIV Analyst & Investor Event on Tuesday, Gilead Sciences Inc. (NASDAQ:GILD) revealed that it is developing a once-yearly injectable formulation for lenacapavir. The annual formulation is ...
The maturation inhibitors are a class of antiviral drugs for the treatment of infection with HIV.They act by interfering with the maturation of the virus. Specifically, drugs in this class disrupt the final step in the processing of the HIV-1 gag protein, the cleavage of its immediate precursor by the enzyme HIV-1 protease.
Lenacapavir, sold under the brand name Sunlenca, is an antiretroviral medication used to treat HIV/AIDS. [9] [10] It is taken by mouth or by subcutaneous injection.[9] [10]The most common side effects include reactions at the injection site and nausea.
Antiretroviral drugs are used to manage HIV/AIDS.Multiple antiretroviral drugs are often combined into a single pill in order to reduce pill burden.. Some of these combinations are complete single-tablet regimens; the others must be combined with additional pills to make a treatment regimen.