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  2. Polygene - Wikipedia

    en.wikipedia.org/wiki/Polygene

    A polygene is a member of a group of non-epistatic genes that interact additively to influence a phenotypic trait, thus contributing to multiple-gene inheritance (polygenic inheritance, multigenic inheritance, quantitative inheritance [1]), a type of non-Mendelian inheritance, as opposed to single-gene inheritance, which is the core notion of Mendelian inheritance.

  3. Phenotype - Wikipedia

    en.wikipedia.org/wiki/Phenotype

    Here the relation between genotype and phenotype is illustrated, using a Punnett square, for the character of petal color in pea plants. The letters B and b represent genes for color, and the pictures show the resultant phenotypes. This shows how multiple genotypes (BB and Bb) may yield the same phenotype (purple petals).

  4. Complex traits - Wikipedia

    en.wikipedia.org/wiki/Complex_traits

    Complex traits are also known as polygenic traits and multigenic traits. [1] [2] The existence of complex traits, which are far more common than Mendelian traits, represented a significant challenge to the acceptance of Mendel's work. Modern understanding has 3 categories of complex traits: quantitative, meristic, and threshold.

  5. Genetic architecture - Wikipedia

    en.wikipedia.org/wiki/Genetic_architecture

    Genetic architecture is the underlying genetic basis of a phenotypic trait and its variational properties. [1] Phenotypic variation for quantitative traits is, at the most basic level, the result of the segregation of alleles at quantitative trait loci (QTL) . [ 2 ]

  6. Phenotype microarray - Wikipedia

    en.wikipedia.org/wiki/Phenotype_microarray

    High-throughput phenotypic testing is increasingly important for exploring the biology of bacteria, fungi, yeasts, and animal cell lines such as human cancer cells.Just as DNA microarrays and proteomic technologies have made it possible to assay the expression level of thousands of genes or proteins all a once, phenotype microarrays (PMs) make it possible to quantitatively measure thousands of ...

  7. Phenotypic integration - Wikipedia

    en.wikipedia.org/wiki/Phenotypic_integration

    Phenotypic integration is a metric for measuring the correlation of multiple functionally-related traits to each other. [1] Complex phenotypes often require multiple traits working together in order to function properly. Phenotypic integration is significant because it provides an explanation as to how phenotypes are sustained by relationships ...

  8. Molecular phenotyping - Wikipedia

    en.wikipedia.org/wiki/Molecular_phenotyping

    Furthermore, molecular phenotyping can be applicable to compounds with a range of binding specificities and is able to triage false positives derived from high-content screening assays. Furthermore, molecular phenotyping allows integration of data derived from in vitro and in vivo models as well as patient data into the drug discovery process.

  9. Genomics of personality traits - Wikipedia

    en.wikipedia.org/wiki/Genomics_of_personality_traits

    For humans, the Big Five personality traits, also known as the five-factor model (FFM) or the OCEAN model, is the prevailing model for personality traits. When factor analysis (a statistical technique) is applied to personality survey data, some words or questionnaire items used to describe aspects of personality are often applied to the same person.