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4-Chloroaniline is used in the industrial production of pesticides, drugs, and dyestuffs. It is a precursor to the widely used antimicrobial and bacteriocide chlorhexidine and is used in the manufacture of pesticides, including pyraclostrobin , anilofos , monolinuron , and chlorphthalim .
4-Chloro-o-toluidine (4-COT, 4-chloro-2-methylaniline) is the organic compound with the formula CH 3 C 6 H 3 Cl(NH 2). It is a colorless solid. The compound is produced as an intermediate to the pesticide chlordimeform and a precursor to some azo dyes. Production has declined after it was shown to be highly carcinogenic.
The pesticide manual provides much information on pesticides. [6] [7] Many of the insecticides in the list are not in use. The developer of a pesticide applies for a common name when they intend to sell it, but some nevertheless do not reach the market. Many insecticides have been banned or otherwise withdrawn from the market over the decades.
4,4′-Methylenebis(2-chloroaniline) (also known as MOCA, MBOCA, and bisamine) is a substance used as a curing agent in polyurethane production. [3] MOCA is an aromatic amine which is structurally similar to benzidine , a known human bladder carcinogen.
Based on government tests of pesticide levels, here is the Environmental Working Group’s 2024 list of the produce with the highest and lowest levels of pesticides.
Some organochlorides are considered safe enough for consumption in foods and medicines. For example, peas and broad beans contain the natural chlorinated plant hormone 4-chloroindole-3-acetic acid (4-Cl-IAA); [16] [17] and the sweetener sucralose (Splenda) is widely used in diet products.
The Pesticide Survey, USA 1987 through 1996, reports that the total annual domestic agricultural usage of dicofol averaged about 860,000 pounds active ingredient (a.i.) for about 720,000 acres (2,900 km 2) treated. Most of the area is treated with 2 pounds a.i. or less per application, and the average acre is treated with about 1.2 pounds a.i ...
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