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  2. In 2002, a second risk-management program, the System to Manage Accutane-Related Teratogenicity (SMART), was instituted, introducing a requirement of two negative pregnancy tests before starting ...

  3. Congenital syphilis - Wikipedia

    en.wikipedia.org/wiki/Congenital_syphilis

    Congenital syphilis is syphilis that occurs when a mother with untreated syphilis passes the infection to her baby during pregnancy or at birth. [4] It may present in the fetus , infant , or later. [ 1 ] [ 5 ] Clinical features vary and differ between early onset, that is presentation before 2-years of age, and late onset, presentation after ...

  4. Isotretinoin - Wikipedia

    en.wikipedia.org/wiki/Isotretinoin

    Isotretinoin, also known as 13-cis-retinoic acid and sold under the brand name Accutane among others, is a medication used to treat skin diseases like harlequin-type ichthyosis, and lamellar ichthyosis, and severe cystic acne or moderate acne that is unresponsive to antibiotics. [6]

  5. Accutane can be an effective solution for combating moderate to severe acne, but it comes with a unique set of instructions and some uncomfortable side effects. One reaction many Accutane users ...

  6. iPLEDGE program - Wikipedia

    en.wikipedia.org/wiki/IPLEDGE_program

    Once a doctor decides a patient is a candidate for isotretinoin, [10] they counsel the patient to ensure they understand the drug and the potential side effects. Once the patient signs the necessary paperwork, their doctor will give them a patient ID number, ID card, and program educational materials.

  7. As syphilis cases among US newborns soar, doctors group ... - AOL

    www.aol.com/news/syphilis-cases-among-us...

    With syphilis cases in U.S. newborns skyrocketing, a doctors group now recommends that all pregnant patients be screened three times for the sexually transmitted infection. The American College of ...

  8. History of syphilis - Wikipedia

    en.wikipedia.org/wiki/History_of_syphilis

    Unpleasant side effects of mercury treatment included gum ulcers and loose teeth. [68] Mercury continued to be used in syphilis treatment for centuries; an 1869 article by Thomas James Walker, M. D., discussed administering mercury by injection for this purpose. [69] The discovery of guaiacum as cure for syphilis, after Stradanus, 1590

  9. Syphilis - Wikipedia

    en.wikipedia.org/wiki/Syphilis

    Syphilis has been known as "the great imitator", because it may cause symptoms similar to many other diseases. [2] [3] Syphilis is most commonly spread through sexual activity. [2] It may also be transmitted from mother to baby during pregnancy or at birth, resulting in congenital syphilis.