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  2. Cereblon E3 ligase modulator - Wikipedia

    en.wikipedia.org/wiki/Cereblon_E3_ligase_modulator

    Pomalidomide (3-aminothalidomide) was the second thalidomide analog to enter the clinic being more potent than both of its predecessors. [12] First reported in 2001, pomalidomide was noted to directly inhibit myeloma cell proliferation and thus inhibiting MM both on the tumor and vascular compartments. [ 13 ]

  3. Pomalidomide - Wikipedia

    en.wikipedia.org/wiki/Pomalidomide

    Pomalidomide, sold under the brand names Pomalyst and Imnovid, [7] [8] is an anti-cancer medication used for the treatment of multiple myeloma and AIDS-related Kaposi sarcoma. [ 7 ] Pomalidomide was approved for medical use in the United States in February 2013, [ 10 ] and in the European Union in August 2013. [ 8 ]

  4. Pomalyst Takes the Stage - AOL

    www.aol.com/news/2013-02-21-pomalyst-takes-the...

    Patients taking Pomalyst must have previously tried Celgene's top drug, Revlimid, and Velcade -- developed by Johnson & Johnson and Takeda. Celgene rightly views Pomalyst as a complementary ...

  5. Lenalidomide - Wikipedia

    en.wikipedia.org/wiki/Lenalidomide

    Lenalidomide, sold under the brand name Revlimid among others, is a medication used to treat multiple myeloma, smoldering myeloma, and myelodysplastic syndromes (MDS). [8] For multiple myeloma, it is a first line treatment, and is given with dexamethasone. [8] It is taken by mouth. [8]

  6. Pomalyst Takes the Stage - AOL

    www.aol.com/news/2013-05-14-pomalyst-takes-the...

    The answer is Pomalyst. Its parent has one of the longest and varied histories in the annals of medicine. Its sibling is a star raking in billions of dollars every year. And now it stands ready to ...

  7. Elotuzumab - Wikipedia

    en.wikipedia.org/wiki/Elotuzumab

    The elotuzumab group, with 60 patients, received elotuzumab with pomalidomide and dexamethasone and the control group, with 57 patients, received pomalidomide and dexamethasone alone. [12] Among patients that had failed treatment with lenalidomide and a protease inhibitor, death or risk of progression was significantly lower in the elotuzumab ...

  8. 5 cancer types where screenings save the most lives - AOL

    www.aol.com/5-cancer-types-where-screenings...

    Over a 45-years span — between 1975 and 2020 — improvements in cancer screenings and prevention strategies have reduced deaths from five common cancers more than any advances in treatments ...

  9. Obstructive lung disease - Wikipedia

    en.wikipedia.org/wiki/Obstructive_lung_disease

    Many patients eventually require oxygen supplementation at home. In severe cases that are difficult to control, chronic treatment with oral corticosteroids may be necessary, although this is fraught with significant side effects. COPD is generally irreversible although lung function can partially recover if the patient stops smoking.

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