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Stem cells, as a concept, originated as a theory in the 19th century to potentially allow certain tissues to self-renew. There are five types of stem cells, and MSC's are multi-potent, meaning they are cells that have the ability to develop into more than one type of specialized cell. Mesenchymal stem cells were originally discovered and ...
Stem cells enable surgeons to grow replacement cartilage, which gives the new tissue greater growth potential. [ 11 ] [ 12 ] While there are few long-term studies as of 2018, a history of knee problems [ 13 ] and body weight are factors for how well the procedure will work.
Stem-cell therapy uses stem cells to treat or prevent a disease or condition. [1] As of 2024, the only FDA-approved therapy using stem cells is hematopoietic stem cell transplantation. [2] [3] This usually takes the form of a bone marrow or peripheral blood stem cell transplantation, but the cells can also be derived from umbilical cord blood.
Autologous Matrix Induced Chondrogenesis (AMIC) surgery is a single step procedure. After arthroscopic evaluation of the cartilage damage and decision for an AMIC procedure a mini arthrotomy is performed. An all-arthroscopic AMIC procedure for repair of cartilage defects of the knee is also possible. [4]
ACI provides pain relief while at the same time slowing down the progression or considerably delaying partial or total joint replacement (knee replacement) surgery. ACI procedures aim to provide complete hyaline repair tissues for articular cartilage repair. Over the last 20 years, the procedure has become more widespread and it is currently ...
The use of human pluripotent stem cells, specifically induced pluripotent stem cells, offers the cultivation of personalized tissues that minimize rejection risks. [34] Moreover, they enable direct tissue repair within the body, potentially sidestepping the need for surgery and reducing infection risks.
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