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The insufflation of cocaine crystals may also cause physical trauma to epithelial cells, leading to inflammatory lesions, which may also worsen due to the tendency for patients to physically remove the scabs produced in the damaged tissue, which induces further mechanical damage. [6] Cocaine is capable of inducing apoptosis of epithelial cells ...
Levamisole has become a common additive to illicit cocaine. It is thought to intensify the "high" by releasing dopamine in the brain, acts as a bulking agent, and is a difficult adulterant to recognize. Potential risks of levamisole-laced cocaine include neutropenia, agranulocytosis, arthralgias, retiform purpura, skin necrosis, and fever.
Any damage to the inside of the nose is due to cocaine constricting blood vessels — and therefore restricting blood and oxygen/nutrient flow — to that area. Rolled up banknotes, hollowed-out pens, cut straws, pointed ends of keys, specialized spoons, [57] long fingernails, and (clean) tampon applicators are often used to insufflate cocaine.
Troubled comedian Artie Lange, 51, revealed he would be attending rehab after testing positive for multiple drugs, including cocaine, while serving his four-year probation for heroin possession.
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Saddle nose is a condition associated with nasal trauma, congenital syphilis, relapsing polychondritis, granulomatosis with polyangiitis, cocaine abuse, and leprosy, among other conditions. [1] The most common cause is nasal trauma. It is characterized by a loss of height of the nose, because of the collapse of the nasal bridge. The depressed ...
Cocaine and methamphetamine, for example, both increase levels of dopamine in the brain, albeit through different processes. As a result, people using cocaine may respond and behave very ...
Cocaine increases alertness, feelings of well-being, euphoria, energy, sociability, and sexuality. The former are some of the desired effects of cocaine intoxication. Not having the normal use of mental faculties by reason of the introduction of cocaine is defined drug intoxication by the laws in America, Europe, and most of the rest of the World, and it is a serious crime in specific contexts ...