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  2. Acid dissociation constant - Wikipedia

    en.wikipedia.org/wiki/Acid_dissociation_constant

    Nitric acid, with a pK value of around −1.7, behaves as a strong acid in aqueous solutions with a pH greater than 1. [23] At lower pH values it behaves as a weak acid. pK a values for strong acids have been estimated by theoretical means. [24] For example, the pK a value of aqueous HCl has been estimated as −9.3.

  3. Protein pKa calculations - Wikipedia

    en.wikipedia.org/wiki/Protein_pKa_calculations

    See Amino acid for the pK a values of all amino acid side chains inferred in such a way. There are also numerous experimental studies that have yielded such values, for example by use of NMR spectroscopy. The table below lists the model pK a values that are often used in a protein pK a calculation, and contains a third column based on protein ...

  4. Acid strength - Wikipedia

    en.wikipedia.org/wiki/Acid_strength

    Acid strength is the tendency of an acid, symbolised by the chemical formula, to dissociate into a proton, +, and an anion, .The dissociation or ionization of a strong acid in solution is effectively complete, except in its most concentrated solutions.

  5. Dissociation constant - Wikipedia

    en.wikipedia.org/wiki/Dissociation_constant

    In the case of multiple pK values they are designated by indices: pK 1, pK 2, pK 3 and so on. For amino acids, the pK 1 constant refers to its carboxyl (–COOH) group, pK 2 refers to its amino (–NH 2) group and the pK 3 is the pK value of its side chain.

  6. Ion trapping - Wikipedia

    en.wikipedia.org/wiki/Ion_trapping

    The converse is true in a basic medium. For example, Naproxen is a non-steroidal anti-inflammatory drug that is a weak acid (its pKa value is 5.0). The gastric juice has a pH of 2.0. It is a three-fold difference (due to log scale) between its pH and its pKa; therefore there is a 1000× difference between the charged and uncharged concentrations.

  7. Carbanion - Wikipedia

    en.wikipedia.org/wiki/Carbanion

    These values below are pK a values determined in dimethylsulfoxide (DMSO), which has a broader useful range (~0 to ~35) than values determined in water (~0 to ~14) and better reflect the basicity of the carbanions in typical organic solvents. Values below less than 0 or greater than 35 are indirectly estimated; hence, the numerical accuracy of ...

  8. Fluoroantimonic acid - Wikipedia

    en.wikipedia.org/wiki/Fluoroantimonic_acid

    Fluoroantimonic acid is the strongest superacid based on the measured value of its Hammett acidity function (H 0), which has been determined for various ratios of HF:SbF 5. The H 0 of HF is −15. [5] A solution of HF containing 1 mol % of SbF 5 is −20. The H 0 is −21 for 10 mol%. For > 50 mol % SbF 5, the H 0 is between −21 and −23.

  9. Carborane acid - Wikipedia

    en.wikipedia.org/wiki/Carborane_acid

    Carborane acids H(CXB 11 Y 5 Z 6) (X, Y, Z = H, Alk, F, Cl, Br, CF 3) are a class of superacids, [1] some of which are estimated to be at least one million times stronger than 100% pure sulfuric acid in terms of their Hammett acidity function values (H 0 ≤ –18) and possess computed pK a values well below –20, establishing them as some of the strongest known Brønsted acids.