Search results
Results from the WOW.Com Content Network
4-Phenylpiperidine is a chemical compound. It features a benzene ring bound to a piperidine ring. 4-Phenylpiperidine is the base structure for a variety of opioids , such as pethidine (meperidine), ketobemidone , alvimopan , loperamide , and diphenoxylate .
Pyridine and poly(4-vinyl) pyridine have been shown to form conducting molecular wires with remarkable polyenimine structure on UV irradiation, a process which accounts for at least some of the visible light absorption by aged pyridine samples. These wires have been theoretically predicted to be both highly efficient electron donors and ...
4,4′-Bipyridine (abbreviated to 4,4′-bipy or 4,4′-bpy) is an organic compound with the formula (C 5 H 4 N) 2. It is one of several isomers of bipyridine. It is a colorless solid that is soluble in organic solvents. is mainly used as a precursor to N,N′-dimethyl-4,4′-bipyridinium [(C 5 H 4 NCH 3) 2] 2+, known as paraquat.
4-PPBP is a neuroprotective cyclic amine which binds to sigma receptors. [ 1 ] 4-PPBP decreases neuronal nitric oxide synthase (nNOS) activity and ischemia -evoked nitric oxide (NO) production. 4-PPBP provides neuroprotection ; this involves the prevention of ischemia-induced intracellular Ca 2+ dysregulation.
MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) is an organic compound. It is classified as a tetrahydropyridine . It is of interest as a precursor to the monoaminergic neurotoxin MPP + , which causes permanent symptoms of Parkinson's disease by destroying dopaminergic neurons in the substantia nigra of the brain .
In enzymology, the -norcoclaurine synthase (EC 4.2.1.78) is an enzyme that catalyzes a biological Pictect-Spengler synthesis: 1,2,3,4-Tetrahidroisoquinolines biosynthesis: in (S)-norcoclaurine synthase, the two substrates are 4-hydroxyphenylacetaldehyde and 4-(2-aminoethyl)benzene-1,2-diol, whereas its two products are (S)-norcoclaurine and H 2 O.
Picenadol (LY-97435) is a 4-phenyl piperidine derivative that is an opioid analgesic drug developed by Eli Lilly in the 1970s. [1] Picenadol is an effective analgesic with similar efficacy to pethidine (meperidine). It has been investigated for some applications such as obstetrics [2] and dentistry, [3] but never commercialised.
4-Benzylpiperidine is a drug and research chemical used in scientific studies. ... [4] Catalytic hydrogenation of the pyridine ring then completes the synthesis. [5]