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The intestine is also called the bowel or the gut. The lower GI starts at the pyloric sphincter of the stomach and finishes at the anus. The small intestine is subdivided into the duodenum, the jejunum and the ileum. The cecum marks the division between the small and large intestine. The large intestine includes the rectum and anal canal. [2]
The large intestine houses over 700 species of bacteria that perform a variety of functions, as well as fungi, protozoa, and archaea. Species diversity varies by geography and diet. [ 46 ] The microbes in a human distal gut often number in the vicinity of 100 trillion, and can weigh around 200 grams (0.44 pounds).
For example, certain strains in the large intestine produce vitamin B 12; [41] an essential compound in humans for things like DNA synthesis and red blood cell production. [42] However, the primary function of the large intestine is water absorption from digested material (regulated by the hypothalamus) and the reabsorption of sodium and ...
Mucus is released in the stomach and intestine, and serves to lubricate and protect the inner mucosa of the tract. It is composed of a specific family of glycoproteins termed mucins and is generally very viscous. Mucus is made by two types of specialized cells termed mucous cells in the stomach and goblet cells in the intestines. Signals for ...
The large intestine's main function is to transport food particles through the body and expel the indigestible parts at the other end, but it also collects waste from throughout the body. The typical brown colour of mammal waste is due to bilirubin, a breakdown product of normal heme catabolism. [1]
An organ system is a biological system consisting of a group of organs that work together to perform one or more functions. [1] Each organ has a specialized role in an organism body, and is made up of distinct tissues.
Intestinal stem cell aging has been studied in Drosophila as a model for understanding the biology of stem cell/niche aging. [4] Using knockdown mutants defective in various genes that function in the DNA damage response in enterocytes, it was shown that deficiency in the DNA damage response accelerates intestinal stem cell aging, thus ...
The intestinal epithelium is the single cell layer that forms the luminal surface (lining) of both the small and large intestine (colon) of the gastrointestinal tract. Composed of simple columnar epithelium its main functions are absorption, and secretion. Useful substances are absorbed into the body, and the entry of harmful substances is ...