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2. Portosystemic shunts in animals - Wikipedia

   en.wikipedia.org/wiki/Portosystemic_shunts_in...

   All forms of portosystemic shunts produce various neurological, gastrointestinal, and urinary symptoms. [3]Symptoms of congenital PSS usually appear by six months of age [4] and include failure to gain weight, vomiting, and signs of hepatic encephalopathy (a condition where toxins normally removed by the liver accumulate in the blood and impair the function of brain cells) such as seizures ...

3. Detoxification - Wikipedia

   en.wikipedia.org/wiki/Detoxification

   The liver and kidney are naturally capable of detox, as are intracellular (specifically, inner membrane of mitochondria or in the endoplasmic reticulum of cells) proteins such as CYP enzymes. In cases of kidney failure , the action of the kidneys is mimicked by dialysis ; kidney and liver transplants are also used for kidney and liver failure ...

4. Drug metabolism - Wikipedia

   en.wikipedia.org/wiki/Drug_metabolism

   Drug metabolism is the metabolic breakdown of drugs by living organisms, usually through specialized enzymatic systems. More generally, xenobiotic metabolism (from the Greek xenos "stranger" and biotic "related to living beings") is the set of metabolic pathways that modify the chemical structure of xenobiotics, which are compounds foreign to an organism's normal biochemistry, such as any drug ...

5. Arsenic poisoning - Wikipedia

   en.wikipedia.org/wiki/Arsenic_poisoning

   Arsenic poisoning (or arsenicosis) is a medical condition that occurs due to elevated levels of arsenic in the body. [4] If arsenic poisoning occurs over a brief period of time, symptoms may include vomiting, abdominal pain, encephalopathy, and watery diarrhea that contains blood. [1]

6. Proteins produced and secreted by the liver - Wikipedia

   en.wikipedia.org/wiki/Proteins_produced_and...

   All plasma proteins except Gamma-globulins are synthesised in the liver. [1] Human serum albumin, osmolyte and carrier protein; α-fetoprotein, the fetal counterpart of serum albumin; Soluble plasma fibronectin, forming a blood clot that stops bleeding; C-reactive protein, opsonin on microbes, [2] acute phase protein; Various other globulins

7. Congenital portosystemic shunt - Wikipedia

   en.wikipedia.org/wiki/Congenital_Portosystemic_shunt

   The presence of a shunt, a bypass of the liver, causes blood to flow directly to the heart. This blood is no longer filtered by the liver and reaches the systemic circulation , resulting in a number of symptoms and complications with effects on the cardiovascular , neurophysiological , gastro-intestinal , urinary and endocrinal systems .