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2. Levothyroxine - Wikipedia

   en.wikipedia.org/wiki/Levothyroxine

   Levothyroxine has a half-life of 7.5 days when taken daily, so about six weeks is required for it to reach a steady level in the blood. [5] Side effects from excessive doses include weight loss, trouble tolerating heat, sweating, anxiety, trouble sleeping, tremor, and fast heart rate. [5]

3. Loading dose - Wikipedia

   en.wikipedia.org/wiki/Loading_dose

   So, the maintenance dose of foosporin is 100 milligrams (100 mg) per day—just enough to offset the amount cleared. Suppose a patient just started taking 100 mg of foosporin every day. On the first day, they'd have 100 mg in their system; their body would clear 10 mg, leaving 90 mg.

4. Hypothyroidism - Wikipedia

   en.wikipedia.org/wiki/Hypothyroidism

   Blood free thyroxine and TSH levels are monitored to help determine whether the dose is adequate. This is done 4–8 weeks after the start of treatment or a change in levothyroxine dose. Once the adequate replacement dose has been established, the tests can be repeated after 6 and then 12 months, unless there is a change in symptoms. [8]

5. Thyroid hormones - Wikipedia

   en.wikipedia.org/wiki/Thyroid_hormones

   Levothyroxine is the chemical name of the manufactured version of T 4, which is metabolised more slowly than T 3 and hence usually only needs once-daily administration. Natural desiccated thyroid hormones are derived from pig thyroid glands, and are a "natural" hypothyroid treatment containing 20% T 3 and traces of T 2, T 1 and calcitonin.

6. Effective dose (pharmacology) - Wikipedia

   en.wikipedia.org/wiki/Effective_dose_(pharmacology)

   The median effective dose is the dose that produces a quantal effect (all or nothing) in 50% of the population that takes it (median referring to the 50% population base). [6] It is also sometimes abbreviated as the ED 50, meaning "effective dose for 50% of the population". The ED50 is commonly used as a measure of the reasonable expectancy of ...

7. Thyroid disease - Wikipedia

   en.wikipedia.org/wiki/Thyroid_disease

   Thyroid disease is a medical condition that affects the structure and/or function of the thyroid gland.The thyroid gland is located at the front of the neck and produces thyroid hormones [1] that travel through the blood to help regulate many other organs, meaning that it is an endocrine organ.

8. Thyroid-stimulating hormone - Wikipedia

   en.wikipedia.org/wiki/Thyroid-stimulating_hormone

   Thyroid-stimulating hormone (also known as thyrotropin, thyrotropic hormone, or abbreviated TSH) is a pituitary hormone that stimulates the thyroid gland to produce thyroxine (T 4), and then triiodothyronine (T 3) which stimulates the metabolism of almost every tissue in the body. [1]

9. Clark's rule - Wikipedia

   en.wikipedia.org/wiki/Clark's_rule

   The procedure is to take the child's weight in pounds, divide by 150 lb, and multiply the fractional result by the adult dose to find the equivalent child dosage.For example, if an adult dose of medication calls for 30 mg and the child weighs 30 lb, divide the weight by 150 (30/150) to obtain 1/5 and multiply 1/5 times 30 mg to get 6 mg.