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This list of over 500 monoclonal antibodies includes approved and investigational drugs as well as drugs that have been withdrawn from market; consequently, the column Use does not necessarily indicate clinical usage. See the list of FDA-approved therapeutic monoclonal antibodies in the monoclonal antibody therapy page.
Pagoclone is an anxiolytic agent from the cyclopyrrolone family, related to better-known drugs such as the sleeping medication zopiclone.It was synthesized by a French team working for Rhone-Poulenc & Rorer S.A. [1] Pagoclone belongs to the class of nonbenzodiazepines, which have similar effects to the older benzodiazepine group, but with quite different chemical structures.
An anti-asthmatic agent, also known as an anti-asthma drug, refers to a drug that can aid in airway smooth muscle dilation to allow normal breathing during an asthma attack or reduce inflammation on the airway to decrease airway resistance for asthmatic patients, or both. The goal of asthmatic agents is to reduce asthma exacerbation frequencies ...
The US Food and Drug Administration on Friday approved a medication called Xolair to help lessen the severity of an accidental allergic reaction in people who are allergic to multiple foods.
Currently, the U.S. Food and Drug Administration has not approved any oral immunotherapy agents for asthma. [22] In January 2020, the FDA approved Palforzia for mitigating "allergic reactions, including anaphylaxis, that may occur with accidental exposure to peanuts." [23] [24] It is the first drug approved for peanut allergies. It will not ...
On February 18, 2011, the FDA issued a safety alert for long-acting β agonists. [24] Following new clinical safety trials, the FDA issued updated guidance on 20 December 2017, that there is no significant increased risk of serious asthma outcomes with LABAs when used together with inhaled corticosteroids. [25]
Tezepelumab, sold under the brand name Tezspire, is a human monoclonal antibody used for the treatment of asthma. [5] [7] [8] [9] Tezepelumab blocks thymic stromal lymphopoietin (TSLP), [5] an epithelial cytokine that has been suggested to be critical in the initiation and persistence of airway inflammation.
In contrast, pramipexole the (S)-enantiomer is a dopamine agonist and is an approved drug (Mirapex) used in Parkinson's disease. Dexpramipexole is a low molecular weight, orally bioavailable, water-soluble small molecule with linear pharmacokinetics and linear dose proportionality.
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