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Diphenhydramine, while traditionally known as an antagonist, acts primarily as an inverse agonist of the histamine H 1 receptor. [86] It is a member of the ethanolamine class of antihistaminergic agents. [45] By reversing the effects of histamine on the capillaries, it can reduce the intensity of allergic symptoms.
Antihistamines that target the histamine H 1 -receptor are used to treat allergic reactions in the nose (e.g., itching, runny nose, and sneezing). In addition, they may be used to treat insomnia, motion sickness, or vertigo caused by problems with the inner ear. H 2 -antihistamines bind to histamine H 2 receptors in the upper gastrointestinal ...
A medical condition such as stroke affecting the brainstem. Voluntary breath-holding or underbreathing, for example, hypoventilation training [2] or the Buteyko method. Medication or drugs, typically when taken in accidental or intentional overdose. Opioids and benzodiazepines in particular are known to cause respiratory depression.
Here's More Evidence That Common Drugs May Cause Cognition Issues. If you've ever popped a Benadryl or two to sleep through a long flight (or even just a regular night), you can pretty much count ...
The most common symptoms of overdose include central nervous system (CNS) depression, impaired balance, ataxia, and slurred speech. Severe symptoms include coma and respiratory depression. Supportive care is the mainstay of treatment of benzodiazepine overdose. There is an antidote, flumazenil, but its use is controversial. [2]
Benadryl Dry, Tickly Cough Liquid is a cough medicine found in Australia. It is used to temporarily relieve irritating coughs. Pholcodine is the main ingredient found in this cough liquid. [11] This medication is to be taken orally and may cause drowsiness. In India, Benadryl can also be found in the form of a cough liquid and also cough lozenges.
Substance which blocks the action of the acetylcholine (ACh) neurotransmitter. Anticholinergics (anticholinergic agents) are substances that block the action of the acetylcholine (ACh) neurotransmitter at synapses in the central and peripheral nervous system. [1][2] These agents inhibit the parasympathetic nervous system by selectively blocking ...
Some elements of the cholinergic crisis can be reversed with antimuscarinic drugs like atropine or diphenhydramine, but the most dangerous effect - respiratory depression, cannot. [ 6 ] The neuromuscular junction, where the brain communicates with muscles (like the diaphragm , the main breathing muscle), works by acetylcholine activating ...