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Trigeminal neuralgia (TN or TGN), also called Fothergill disease, tic douloureux, trifacial neuralgia, or suicide disease, is a long-term pain disorder that affects the trigeminal nerve, [7] [1] the nerve responsible for sensation in the face and motor functions such as biting and chewing.
Microvascular decompression (MVD), also known as the Jannetta procedure, [1] is a neurosurgical procedure used to treat trigeminal neuralgia (along with other cranial nerve neuralgias), a pain syndrome characterized by severe episodes of intense facial pain, and hemifacial spasm.
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Hence, the TVS has provided a template for migraine pathophysiology and target for drug discovery. The history of some discoveries re the TV System are summarised in Ashina, et al. [ 13 ] The Brain Prize for 2021 was awarded to 4 investigators studying the trigeminovascular system and its implications for migraine pathophysiology and treatments.
The trigeminal nerve.. ATN is usually attributed to inflammation or demyelination, with increased sensitivity of the trigeminal nerve.These effects are believed to be caused by infection, demyelinating diseases, or compression of the trigeminal nerve (by an impinging vein or artery, a tumor, dental trauma, accidents, or arteriovenous malformation) and are often confused with dental problems.
The superior cerebellar artery is frequently the cause of trigeminal neuralgia. It compresses the trigeminal nerve (CN V), causing pain on the patient's face (the distribution of the nerve). This may be treated with vascular microsurgery to decompress the trigeminal nerve. [2] At autopsy, 50% of people without trigeminal neuralgia will also be ...
The jaw jerk reflex or the masseter reflex is a stretch reflex used to test the status of a patient's trigeminal nerve (cranial nerve V) and to help distinguish an upper cervical cord compression from lesions that are above the foramen magnum.
The trigeminal ganglion contains cell bodies of the pseudo-unipolar sensory neurons of the trigeminal nerve which extend their axons both distally/peripherally into the three divisions of the trigeminal nerve on the one end, and proximally/centrally to the brainstem on the other end; the trigeminal root extends from the trigeminal ganglion to the ventrolateral aspect of the pons.