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Faecal calprotectin (or fecal calprotectin) is a biochemical measurement of the protein calprotectin in the stool. Elevated faecal calprotectin indicates the migration of neutrophils to the intestinal mucosa , which occurs during intestinal inflammation, including inflammation caused by inflammatory bowel disease .
Lactoferrin is a globular glycoprotein with a molecular mass of about 80 kDa that is widely represented in various secretory fluids, such as milk, saliva, tears, and nasal secretions. Lactoferrin is also present in secondary granules of PMNs and is secreted by some acinar cells. Lactoferrin can be purified from milk or produced recombinantly.
Fecal calprotectin is 88% sensitive and 79% specific for the diagnosis of ulcerative colitis. [19] If the fecal calprotectin is low, the likelihood of inflammatory bowel disease are less than 1 percent. [12] Lactoferrin is an additional nonspecific marker of intestinal inflammation. [78]
Fecal occult blood testing (FOBT), as its name implies, aims to detect subtle blood loss in the gastrointestinal tract, anywhere from the mouth to the colon.Positive tests ("positive stool") may result from either upper gastrointestinal bleeding or lower gastrointestinal bleeding and warrant further investigation for peptic ulcers or a malignancy (such as colorectal cancer or gastric cancer).
Fecal contamination of food is another form of fecal-oral transmission. Washing hands properly after changing a baby's diaper or after performing anal hygiene can prevent foodborne illness from spreading. [citation needed] The common factors in the fecal-oral route can be summarized as five Fs: fingers, flies, fields, fluids, and food.
The stool guaiac test involves fasting from iron supplements, red meat (the blood it contains can turn the test positive), certain vegetables (which contain a chemical with peroxidase properties that can turn the test positive), and vitamin C and citrus fruits (which can turn the test falsely negative) for a period of time before the test.
Human feces photographed in a toilet, shortly after defecation.. Human feces (American English) or faeces (British English), commonly and in medical literature more often called stool, [1] are the solid or semisolid remains of food that could not be digested or absorbed in the small intestine of humans, but has been further broken down by bacteria in the large intestine.
Testing of stool samples by real-time polymerase chain reaction is able to detect C. difficile about 93% of the time and when positive is incorrectly positive about 3% of the time. [54] This is more accurate than cytotoxigenic culture or cell cytotoxicity assay. [54] Another benefit is that the result can be achieved within three hours. [54]