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Referring to a common salt of fluoride, sodium fluoride (NaF), the lethal dose for most adult humans is estimated at 5 to 10 g (which is equivalent to 32 to 64 mg elemental fluoride/kg body weight). [ 2 ] [ 3 ] [ 4 ] Ingestion of fluoride can produce gastrointestinal discomfort at doses at least 15 to 20 times lower (0.2–0.3 mg/kg or 10 to 15 ...
Fluoride therapy is the use of fluoride for medical purposes. [2] Fluoride supplements are recommended to prevent tooth decay in children older than six months in areas where the drinking water is low in fluoride. [3] It is typically used as a liquid, pill, or paste by mouth. [4] Fluoride has also been used to treat a number of bone diseases. [5]
In fact, 75% of fluoride intake comes from drinking water with added fluoride and from food and beverages, such as sodas and fruit juice, made with fluoridated water, according to the CDC.
Fluoride or fluorine deficiency is a disorder which may cause increased dental caries [1] and possibly osteoporosis, [2] [3] due to a lack of fluoride in diet. [4] [5] Common dietary sources of fluoride include tea, grape juice, wine, raisins, some seafood, coffee, and tap water that has been fluoridated. [6]
Antifluoridationist literature links fluoride exposure to a wide variety of effects, including AIDS, allergy, Alzheimer's disease, arthritis, cancer, and low IQ, along with diseases of the gastrointestinal tract, kidney, pineal gland, and thyroid, though there is no scientific evidence linking fluoridation to these adverse health effects. [70] [71]
Fluoride's effects depend on the total daily intake of fluoride from all sources. [51] About 70–90% of ingested fluoride is absorbed into the blood, where it distributes throughout the body. In infants 80–90% of absorbed fluoride is retained, with the rest excreted, mostly via urine; in adults about 60% is retained.
Prepare for potential side effects. Taking metformin may cause unpleasant side effects like diarrhea, nausea, and an upset stomach. Taking it with food can reduce the risk.
Topical fluorides are fluoride-containing drugs indicated in prevention and treatment of dental caries, particularly in children's primary dentitions. [1] The dental-protecting property of topical fluoride can be attributed to multiple mechanisms of action, including the promotion of remineralization of decalcified enamel, the inhibition of the cariogenic microbial metabolism in dental plaque ...
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