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Brexpiprazole, sold under the brand name Rexulti among others, is an atypical antipsychotic medication used for the treatment of major depressive disorder, schizophrenia, and agitation associated with dementia due to Alzheimer's disease. [11] [13] [14] The most common side effects include akathisia (a constant urge to move) and weight gain. [12]
If symptoms of discontinuation are severe, or do not respond to symptom management, the antidepressant can be reinstated and then withdrawn more cautiously, or by switching to a drug with a longer half life (e.g., fluoxetine), and then tapering and discontinuing that drug. [21] In severe cases, hospitalization may be required. [2]
On May 11, 2023, the FDA approved brexpiprazole (brand name – Rexulti [4]) as a prescription medication for treatment of agitation in dementia. [5]Medical treatment may begin with a cholinesterase inhibitor, which appears safer than other alternatives although evidence for its efficacy is mixed.
The list price of Rexulti is $1,419 per month. However, people can pay much less through a prescription drug plan (PDP), also known as Medicare Part D.According to the manufacturers of the drug ...
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Rexulti (brexpiprazole) – atypical antipsychotic used to treat mood and psychotic disorders; S. Saphris – atypical antipsychotic used to treat ...
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The symptoms from withdrawal may be even more dramatic when the drug has masked prolonged malnutrition, disease, chronic pain, infections (common in intravenous drug use), or sleep deprivation, conditions that drug abusers often develop as a secondary consequence of the drug. When the drug is removed, these conditions may resurface and be ...