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Itself can be extended into the Expectation conditional maximization either (ECME) algorithm. [33] This idea is further extended in generalized expectation maximization (GEM) algorithm, in which is sought only an increase in the objective function F for both the E step and M step as described in the As a maximization–maximization procedure ...
The EM algorithm consists of two steps: the E-step and the M-step. Firstly, the model parameters and the () can be randomly initialized. In the E-step, the algorithm tries to guess the value of () based on the parameters, while in the M-step, the algorithm updates the value of the model parameters based on the guess of () of the E-step.
A classical approach to this problem is the expectation-maximization algorithm, which alternates computing expected values of the unobserved variables conditional on observed data, with maximizing the complete likelihood (or posterior) assuming that previously computed expected values are correct. Under mild regularity conditions, this process ...
The algorithm uses several types of well known functions: Expectation maximization (EM). EM based heuristic for choosing the EM starting point. Maximum likelihood ratio based (LRT-based) heuristic for determining the best number of model-free parameters. Multi-start for searching over possible motif widths. Greedy search for finding multiple ...
In electrical engineering, statistical computing and bioinformatics, the Baum–Welch algorithm is a special case of the expectation–maximization algorithm used to find the unknown parameters of a hidden Markov model (HMM). It makes use of the forward-backward algorithm to compute the statistics for the expectation step. The Baum–Welch ...
In mathematical optimization, the ordered subset expectation maximization (OSEM) method is an iterative method that is used in computed tomography.. In applications in medical imaging, the OSEM method is used for positron emission tomography (PET), for single-photon emission computed tomography (SPECT), and for X-ray computed tomography (X-ray CT) scans.
Variational Bayes can be seen as an extension of the expectation–maximization (EM) algorithm from maximum likelihood (ML) or maximum a posteriori (MAP) estimation of the single most probable value of each parameter to fully Bayesian estimation which computes (an approximation to) the entire posterior distribution of the parameters and latent ...
A general objective function is optimized during the simulation, most generally the "sum of pairs" maximization function introduced in dynamic programming-based MSA methods. A technique for protein sequences has been implemented in the software program SAGA (Sequence Alignment by Genetic Algorithm) [37] and its equivalent in RNA is called RAGA ...